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RECRUITING Phase 3

A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma

NCT06980480 · View on ClinicalTrials.gov ↗

Study Summary

Multiple myeloma is a cancer of the plasma cells in the bone marrow. The main aim of this study is to learn how well the Immune Globulin Infusion (human), 10 percentage (%) (IGI, 10%) can help prevent infections in participants with multiple myeloma receiving B-cell maturation antigen (BCMA) x cluster of differentiation 3 (CD3) directed bispecific antibody therapy. Participants will be randomly assigned to one of two groups: 1. Primary infection prevention group: They will receive IGI, 10% for 12 months. 2. Secondary infection prevention group: They will only receive IGI, 10% if they develop a serious infection during the 12 months study period. During the study, participants will visit their study clinic 15 times (for 4-week dosing interval) or 19 times (for 3-week dosing interval) and their total participation duration will be up to 14 months (including screening period of up to 8 weeks).

Interventions

  • BIOLOGICAL IGI, 10%

Study Locations (16)

Other

  • Universitaetsklinikum St. Poelten — Sankt Pölten
  • Krankenhaus der Barmherzigen Schwestern Wien — Vienna
  • St. Antonius Ziekenhuis — Nieuwegein
  • Aidport sp. z o.o. — Skorzewo
  • County Hospital (Stafford Hospital) — Stafford

Alabama

  • Infirmary Health - Diagnostic & Medical Clinic (DMC) — Mobile

California

  • Chao Family Comprehensive Cancer Center UCI — Orange

Kansas

  • University of Kansas — Westwood

Maryland

  • University of Maryland | Greenebaum Cancer Center — Baltimore

Michigan

  • Henry Ford Health System — Detroit

Missouri

  • Washington University School of Medicine — St Louis

New York

  • New York Oncology Hematology — Albany

Trial Details

FieldValue
Enrollment Target 183 participants
Start Date 2026-01-14
Est. Completion 2028-09-11
Phase Phase 3

Sponsor

Takeda

387 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06980480

The ClinicalTrials.gov registry entry for NCT06980480 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 183 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Takeda, which has 387 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Multiple Myeloma appearing as the primary indexed condition, and to 1 intervention — of which IGI, 10% is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06980480 reports 16 study locations spanning 12 distinct geographic areas — top geographies include Other, Alabama, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06980480 about?

NCT06980480 is a clinical study titled "A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma". Multiple myeloma is a cancer of the plasma cells in the bone marrow. The main aim of this study is to learn how well the Immune Globulin Infusion (human), 10 percentage (%) (IGI, 10%) can help prevent infections in participants with multiple myeloma receiving B-cell maturation antigen (BCMA) x clus...

What is the current status of trial NCT06980480?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 183 participants. The study started on 2026-01-14. Estimated completion is 2028-09-11.

What conditions does trial NCT06980480 study?

This clinical trial studies the following conditions: Multiple Myeloma, Secondary Immunodeficiency. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06980480?

The interventions under investigation include: IGI, 10% (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06980480?

This trial is sponsored by Takeda, which has 387 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06980480 being conducted?

This trial has 16 study locations across Alabama, California, Kansas, Maryland, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial