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NCT06976372 · ClinicalTrials.gov registry record · Phase 1

A Study to Evaluate AMG 133 Administered Subcutaneously in Participants With Overweight or Obesity

A Phase 1 study, sponsored by Amgen.

Completed
Registry status
Phase 1
Development phase
120
Enrollment target

NCT06976372: Completed Phase 1 study, sponsored by Amgen.

NCT06976372 is a Phase 1 study that has completed, run by Amgen. The registered enrollment target is 120 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (100% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06976372, a Phase 1 study, has completed, sponsored by Amgen.

COMPLETED
Registry status
Phase 1
Development phase
120 participants
Enrollment target

Study Summary

The primary objective of this study is to assess the pharmacokinetics (PK) of AMG 133 after multiple subcutaneous (SC) administrations in participants with overweight or obesity using various dose regimens.

Interventions

  • DRUG AMG 133

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2024-08-20
Est. Completion 2024-12-27
Phase Phase 1
Amgen

558 total trials

What the finished NCT06976372 record still lists

NCT06976372 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (100% higher).

The record links to 0 conditions, and to 1 intervention - of which AMG 133 is the first listed.

NCT06976372 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06976372 about?

NCT06976372 is a clinical study titled "A Study to Evaluate AMG 133 Administered Subcutaneously in Participants With Overweight or Obesity". The primary objective of this study is to assess the pharmacokinetics (PK) of AMG 133 after multiple subcutaneous (SC) administrations in participants with overweight or obesity using various dose regimens.

What is the current status of trial NCT06976372?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 120 participants. The study started on 2024-08-20. Estimated completion is 2024-12-27.

What interventions are being tested in trial NCT06976372?

The interventions under investigation include: AMG 133 (DRUG).

Who is sponsoring clinical trial NCT06976372?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06976372's enrollment target sits among peer trials

120 479th of 2000 higher than 1,503 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06976372, the US trial registry maintained by the National Library of Medicine. NCT06976372 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.