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Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course
NCT06957067 · View on ClinicalTrials.gov ↗
Study Summary
Investigators' overall objective is to compare methods of identifying individuals who may be experiencing challenges in Cognitive Processing Therapy (CPT) and compare methods of intervening to optimize treatment retention and outcomes. Investigators' specific aims are: 1. to determine whether the use of CPT skills versus collaboratively considering switching to Present Centered Therapy (PCT) is more effective in improving outcomes for individuals experiencing challenges with CPT. Outcomes include post-traumatic stress disorder (PTSD) severity \[primary\], depression, functioning, and treatment retention; 2. to compare two approaches to identifying individuals in CPT in need of additional support during treatment; 3. to study the barriers and facilitators of implementing these intervention strategies. Finally, exploratory aims will examine the stability of differences between treatment conditions, compare combinations of interventions tested, and examine moderators of intervention effects.
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Processing Therapy
- BEHAVIORAL CPT Skills
- BEHAVIORAL Present Centered Therapy
- BEHAVIORAL Shared Decision Making
- BEHAVIORAL Measurement Based Care
Study Locations (4)
Arizona
- VA Phoenix Health Care System — Phoenix
Louisiana
- New Orleans VA Medical Center — New Orleans
South Carolina
- Ralph H. Johnson VA Health Care System (Charleston VA) — Charleston
Texas
- VA Houston Healthcare System — Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 280 participants |
| Start Date | 2025-03-17 |
| Est. Completion | 2028-08-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06957067
The ClinicalTrials.gov registry entry for NCT06957067 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 280 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is United States Department of Defense, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 5 interventions — of which Cognitive Processing Therapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06957067 reports 4 study locations spanning 4 distinct geographic areas — top geographies include Arizona, Louisiana, South Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06957067 about?
NCT06957067 is a clinical study titled "Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course". Investigators' overall objective is to compare methods of identifying individuals who may be experiencing challenges in Cognitive Processing Therapy (CPT) and compare methods of intervening to optimize treatment retention and outcomes. Investigators' specific aims are: 1. to determine whether the u...
What is the current status of trial NCT06957067?
This trial is currently recruiting. It is a NA study. The enrollment target is 280 participants. The study started on 2025-03-17. Estimated completion is 2028-08-31.
What conditions does trial NCT06957067 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06957067?
The interventions under investigation include: Cognitive Processing Therapy (BEHAVIORAL), CPT Skills (BEHAVIORAL), Present Centered Therapy (BEHAVIORAL), Shared Decision Making (BEHAVIORAL), Measurement Based Care (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06957067?
This trial is sponsored by United States Department of Defense, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06957067 being conducted?
This trial has 4 study locations across Arizona, Louisiana, South Carolina, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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