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NCT06943846 · ClinicalTrials.gov registry record · NA
Platelet-Rich Fibrinogen in Extraction Socket Healing of the Aged
A NA study of Edentulism, sponsored by University of Nebraska.
- Recruiting
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT06943846: Recruiting NA study of Edentulism, sponsored by University of Nebraska.
NCT06943846 is a NA study of Edentulism that is actively recruiting participants, run by University of Nebraska. The registered enrollment target is 12 participants, below the 192-participant average among 4 other Edentulism trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06943846, a NA study of Edentulism, is actively recruiting participants, sponsored by University of Nebraska.
- RECRUITING
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to better understand oral wound healing in the aged participant following placement of platelet-rich fibrinogen (PRF). In this study, 12 participants requiring a posterior tooth extraction will be enroll: 6 participants aged 14-18, 6 participants aged 50-80. All will undergo a posterior tooth extraction with a small tissue specimen taken from the extraction site. Half of the participants will also have their blood drawn and platelet-rich fibrinogen placed in the extraction socket. Participants will return in 2 weeks for suture removal and another soft tissue sample. Participants will return at 3 months for a final post-operative radiograph. All soft tissue samples will undergo immunofluorescence.
Primary Outcome
Indirect immunofluorescent intensity will determine concentration of cytokines present in sample.
Conditions Studied
Interventions
- PROCEDURE Platelet-rich fibrin (PRF)
Study Locations (1)
Nebraska
- University of Nebraska Medical Center College of Dentistry - Lincoln
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2025-05-01 |
| Est. Completion | 2027-05 |
| Phase | NA |
What NCT06943846 shows while recruiting
NCT06943846 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 192-participant average among 4 other Edentulism trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Edentulism appearing as the primary indexed condition, and to 1 intervention - of which Platelet-rich fibrin (PRF) is the first listed.
NCT06943846 reports a single indexed study location in Nebraska.
Frequently Asked Questions
What is clinical trial NCT06943846 about?
NCT06943846 is a clinical study titled "Platelet-Rich Fibrinogen in Extraction Socket Healing of the Aged". The purpose of this study is to better understand oral wound healing in the aged participant following placement of platelet-rich fibrinogen (PRF). In this study, 12 participants requiring a posterior tooth extraction will be enroll: 6 participants aged 14-18, 6 participants aged 50-80. All will und...
What is the current status of trial NCT06943846?
This trial is currently recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2025-05-01. Estimated completion is 2027-05.
What conditions does trial NCT06943846 study?
This clinical trial studies the following conditions: Edentulism.
What interventions are being tested in trial NCT06943846?
The interventions under investigation include: Platelet-rich fibrin (PRF) (PROCEDURE).
Who is sponsoring clinical trial NCT06943846?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06943846 being conducted?
This trial has 1 study location across Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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