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ACTIVE NOT RECRUITING Phase 3

A Phase 3 Trial of MM120 for Major Depressive Disorder (Emerge)

NCT06941844 · View on ClinicalTrials.gov ↗

Study Summary

A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating MM120 Compared to Placebo in Major Depressive Disorder - Emerge

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG MM120 (LSD D-Tartrate)

Study Locations (20)

Florida

  • Clinical Neuroscience Solutions, Inc — Jacksonville
  • Clinical Neuroscience Solutions, Inc — Orlando
  • Charter Research — Orlando

Arkansas

  • Preferred Research Partner — Fayetteville
  • Preferred Research Partners, Inc — Little Rock

California

  • Kadima Neuropsychiatry Institute — La Jolla
  • Psychedelic Science Institute — Santa Monica

Massachusetts

  • Adams Clinical Boston — Boston
  • Adams Clinical — Watertown

New York

  • Adams Clinical Harlem — New York
  • Columbia - New York State Psychiatric Institute — New York

Ohio

  • Neuro-Behavioral Clinical Research — Canton
  • University of Cincinnati — Cincinnati

Colorado

  • Mountain View Clinical Research, Inc — Denver

Illinois

  • Uptown Research — Chicago

Trial Details

FieldValue
Enrollment Target 149 participants
Start Date 2025-04-14
Est. Completion 2027-05
Phase Phase 3

Sponsor

Definium Therapeutics US

4 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06941844

The ClinicalTrials.gov registry entry for NCT06941844 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 149 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Definium Therapeutics US, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Major Depressive Disorder appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06941844 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Florida, Arkansas, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06941844 about?

NCT06941844 is a clinical study titled "A Phase 3 Trial of MM120 for Major Depressive Disorder (Emerge)". A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating MM120 Compared to Placebo in Major Depressive Disorder - Emerge

What is the current status of trial NCT06941844?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 149 participants. The study started on 2025-04-14. Estimated completion is 2027-05.

What conditions does trial NCT06941844 study?

This clinical trial studies the following conditions: Major Depressive Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06941844?

The interventions under investigation include: Placebo (OTHER), MM120 (LSD D-Tartrate) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06941844?

This trial is sponsored by Definium Therapeutics US, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06941844 being conducted?

This trial has 20 study locations across Arkansas, California, Colorado, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial