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NCT06940141 · ClinicalTrials.gov registry record · Phase 2
Rademikibart Add-on Treatment of an Acute Asthma Exacerbation (Seabreeze STAT Asthma)
A Phase 2 study of Asthma Acute, sponsored by Connect Biopharm.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 160
- Enrollment target
- 20
- Study locations
NCT06940141: Recruiting Phase 2 study of Asthma Acute, sponsored by Connect Biopharm.
NCT06940141 is a Phase 2 study of Asthma Acute that is actively recruiting participants, run by Connect Biopharm. The registered enrollment target is 160 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (20% higher). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06940141, a Phase 2 study of Asthma Acute, is actively recruiting participants, sponsored by Connect Biopharm.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 160 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a Phase 2, randomized, multicenter study in adult and adolescent participants with asthma and type 2 inflammation
Primary Outcome
Treatment failure is defined as death due to any cause, (re)admission to a hospital for asthma, ED (re)visit or unscheduled medical visit for worsening of asthma symptoms, or the necessity to intensify pharmacologic treatment (including second course of systemic steroids for asthma exacerbation) within 28 days after randomization.
Conditions Studied
Interventions
- COMBINATION_PRODUCT Rademikibart in prefilled syringe
- DRUG Matching placebo in prefilled syringe
Study Locations (20)
Florida
- Synergy Healthcare - Bradenton
- Pharmax Research of South Florida, Inc. - Miami
- Columbus Clinical Services, LLC - Miami
- Health Synergy Clinical Research, LLC - West Palm Beach
Texas
- Inquest Clinical Research - Baytown
- Premier Pulmonary Critical Care and Sleep Medicine - Denison
- DCT- McAllen Primary Care Research, LLC dba Discovery Clinical Trials - McAllen
Georgia
- Primeway Clinical Research Group - Fayetteville
- Pivotal Research Solutions - Stonecrest
Buenos Aires
- STAT Research - Caba
- Investigaciones en Alergias y Enfermoedades Respiratorias (InAER) - Caba
Santa Fe Province
- Centro respiratorio Infantil - Rosario
- INECO Neurociencias Oroño - Rosario
California
- Amicis Research Center - Valencia
Iowa
- University of Iowa - Iowa City
Kansas
- University of Kansas Medical Center - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2025-08-08 |
| Est. Completion | 2026-05 |
| Phase | Phase 2 |
What NCT06940141 shows while recruiting
NCT06940141 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (20% higher).
The record links to 1 condition, with Asthma Acute appearing as the primary indexed condition, and to 2 interventions - of which Rademikibart in prefilled syringe is the first listed.
NCT06940141 names 20 study sites across 12 states, led by Florida, Texas, Georgia.
Frequently Asked Questions
What is clinical trial NCT06940141 about?
NCT06940141 is a clinical study titled "Rademikibart Add-on Treatment of an Acute Asthma Exacerbation (Seabreeze STAT Asthma)". This is a Phase 2, randomized, multicenter study in adult and adolescent participants with asthma and type 2 inflammation
What is the current status of trial NCT06940141?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 160 participants. The study started on 2025-08-08. Estimated completion is 2026-05.
What conditions does trial NCT06940141 study?
This clinical trial studies the following conditions: Asthma Acute.
What interventions are being tested in trial NCT06940141?
The interventions under investigation include: Rademikibart in prefilled syringe (COMBINATION_PRODUCT), Matching placebo in prefilled syringe (DRUG).
Who is sponsoring clinical trial NCT06940141?
This trial is sponsored by Connect Biopharm, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06940141 being conducted?
This trial has 20 study locations across California, Florida, Georgia, Iowa, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Asthma Acute
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06940141's enrollment target sits among peer trials
160 422nd of 2000 higher than 1,560 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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