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NCT06926634 · ClinicalTrials.gov registry record · Phase 2

Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)

A Phase 2 study of High Grade Neuroendocrine Neoplasms, sponsored by Washington University School of Medicine.

Recruiting
Registry status
Phase 2
Development phase
32
Enrollment target
2
Study locations

NCT06926634 is a Phase 2 study of High Grade Neuroendocrine Neoplasms that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 32 participants. The trial reports 2 study locations across 2 states.

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The verdict

NCT06926634, a Phase 2 study of High Grade Neuroendocrine Neoplasms, is actively recruiting participants, sponsored by Washington University School of Medicine.

RECRUITING
Registry status
Phase 2
Development phase
32 participants
Enrollment target
2
Study locations

Study Summary

The investigators hypothesize that zanzalintinib maintenance therapy after initial cytotoxic chemotherapy can prolong the progression-free survival (PFS) in patients with high-grade NENs.

Interventions

  • DRUG Zanzalintinib

Study Locations (2)

Minnesota

  • Mayo Clinic - Rochester - Rochester

Missouri

  • Washington University School of Medicine - St Louis

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2025-12-09
Est. Completion 2034-12-31
Phase Phase 2

What the Registry Record Tells You About NCT06926634

The ClinicalTrials.gov registry entry for NCT06926634 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with High Grade Neuroendocrine Neoplasms appearing as the primary indexed condition, and to 1 intervention - of which Zanzalintinib is the first listed.

NCT06926634 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Minnesota, Missouri.

Frequently Asked Questions

What is clinical trial NCT06926634 about?

NCT06926634 is a clinical study titled "Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)". The investigators hypothesize that zanzalintinib maintenance therapy after initial cytotoxic chemotherapy can prolong the progression-free survival (PFS) in patients with high-grade NENs.

What is the current status of trial NCT06926634?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 32 participants. The study started on 2025-12-09. Estimated completion is 2034-12-31.

What conditions does trial NCT06926634 study?

This clinical trial studies the following conditions: High Grade Neuroendocrine Neoplasms.

What interventions are being tested in trial NCT06926634?

The interventions under investigation include: Zanzalintinib (DRUG).

Who is sponsoring clinical trial NCT06926634?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06926634 being conducted?

This trial has 2 study locations across Minnesota, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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