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NCT06924320 · ClinicalTrials.gov registry record · Phase 1

A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes

A Phase 1 study of Obesity and Obesity-related Medical Conditions, sponsored by Metsera, a wholly owned subsidiary of Pfizer.

Recruiting
Registry status
Phase 1
Development phase
132
Enrollment target
1
Study location

NCT06924320: Recruiting Phase 1 study of Obesity and Obesity-related Medical Conditions, sponsored by Metsera, a wholly owned subsidiary of Pfizer.

NCT06924320 is a Phase 1 study of Obesity and Obesity-related Medical Conditions that is actively recruiting participants, run by Metsera, a wholly owned subsidiary of Pfizer. The registered enrollment target is 132 participants, below the 527-participant average among 13 other Obesity and Obesity-related Medical Conditions trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06924320, a Phase 1 study of Obesity and Obesity-related Medical Conditions, is actively recruiting participants, sponsored by Metsera, a wholly owned subsidiary of Pfizer.

RECRUITING
Registry status
Phase 1
Development phase
132 participants
Enrollment target
1
Study location

Study Summary

This study is designed to test how well the combination of MET233 with MET097 works to treat individuals with obesity or overweight with or without diabetes.

Primary Outcome

For Part A, B, C, D, E and G

Interventions

  • DRUG Placebo
  • DRUG MET233 and MET097
  • DRUG MET233

Study Locations (1)

California

  • Research Site MET233/097 24-101-001 - Cypress

Trial Details

FieldValue
Enrollment Target 132 participants
Start Date 2025-03-03
Est. Completion 2027-03-15
Phase Phase 1

What NCT06924320 shows while recruiting

NCT06924320 is an interventional study that assigns participants to a tested intervention. The registered 132 participants enrollment target is mid-sized for trials with a published cap, below the 527-participant average among 13 other Obesity and Obesity-related Medical Conditions trials with a reported enrollment target (75% lower).

The record links to 1 condition, with Obesity and Obesity-related Medical Conditions appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT06924320 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT06924320 about?

NCT06924320 is a clinical study titled "A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes". This study is designed to test how well the combination of MET233 with MET097 works to treat individuals with obesity or overweight with or without diabetes.

What is the current status of trial NCT06924320?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 132 participants. The study started on 2025-03-03. Estimated completion is 2027-03-15.

What conditions does trial NCT06924320 study?

This clinical trial studies the following conditions: Obesity and Obesity-related Medical Conditions.

What interventions are being tested in trial NCT06924320?

The interventions under investigation include: Placebo (DRUG), MET233 and MET097 (DRUG), MET233 (DRUG).

Who is sponsoring clinical trial NCT06924320?

This trial is sponsored by Metsera, a wholly owned subsidiary of Pfizer, which has 7 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06924320 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Obesity and Obesity-related Medical Conditions

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06924320's enrollment target sits among peer trials

132 2nd of 13 the highest of 13 other Obesity and Obesity-related Medical Conditions trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Obesity and Obesity-related Medical Conditions trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06924320, the US trial registry maintained by the National Library of Medicine. NCT06924320 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.