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NCT06919939 · ClinicalTrials.gov registry record · Phase 2

Epcoritamab in Combination With Loncastuximab Tesirine in Relapsed/Refractory Large B-cell Lymphoma

A Phase 2 study of Large B-cell Lymphoma and Relapse, sponsored by University of Miami.

Recruiting
Registry status
Phase 2
Development phase
26
Enrollment target
1
Study location

NCT06919939 is a Phase 2 study of Large B-cell Lymphoma and Relapse that is actively recruiting participants, run by University of Miami. The registered enrollment target is 26 participants, below the 158-participant average among 28 other Large B-cell Lymphoma trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06919939, a Phase 2 study of Large B-cell Lymphoma and Relapse, is actively recruiting participants, sponsored by University of Miami.

RECRUITING
Registry status
Phase 2
Development phase
26 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine whether combining Loncastuximab Tesirine with Epcoritamab is tolerable and effective for reducing and/or eliminating lymphoma cells in the body.

Interventions

  • DRUG Epcoritamab
  • DRUG Loncastuximab Tesirine

Study Locations (1)

Florida

  • University of Miami - Miami

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2026-01-07
Est. Completion 2031-01-07
Phase Phase 2

Sponsor

University of Miami

721 total trials

What the Registry Record Tells You About NCT06919939

The ClinicalTrials.gov registry entry for NCT06919939 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 158-participant average among 28 other Large B-cell Lymphoma trials with a reported enrollment target (84% lower). The listed sponsor is University of Miami, which has 721 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Large B-cell Lymphoma appearing as the primary indexed condition, and to 2 interventions - of which Epcoritamab is the first listed.

NCT06919939 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT06919939 about?

NCT06919939 is a clinical study titled "Epcoritamab in Combination With Loncastuximab Tesirine in Relapsed/Refractory Large B-cell Lymphoma". The purpose of this study is to determine whether combining Loncastuximab Tesirine with Epcoritamab is tolerable and effective for reducing and/or eliminating lymphoma cells in the body.

What is the current status of trial NCT06919939?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 26 participants. The study started on 2026-01-07. Estimated completion is 2031-01-07.

What conditions does trial NCT06919939 study?

This clinical trial studies the following conditions: Large B-cell Lymphoma, Relapse.

What interventions are being tested in trial NCT06919939?

The interventions under investigation include: Epcoritamab (DRUG), Loncastuximab Tesirine (DRUG).

Who is sponsoring clinical trial NCT06919939?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06919939 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Large B-cell Lymphoma

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.