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NCT06898138 · ClinicalTrials.gov registry record · NA
Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations
A NA study, sponsored by Mayo Clinic.
- Not yet
- Registry status
- NA
- Development phase
- 8
- Enrollment target
NCT06898138: Clinical Trial NA study, sponsored by Mayo Clinic.
NCT06898138 is a NA study that has not yet begun recruiting, run by Mayo Clinic. The registered enrollment target is 8 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06898138, a NA study, has not yet begun recruiting, sponsored by Mayo Clinic.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 8 participants
- Enrollment target
Study Summary
Overall, this study will investigate the functional utility of stereotyped HFOs by capturing them with a new implantable system (Brain Interchange - BIC of CorTec), which can sample neural data at higher rates \>=1kHz and deliver targeted electrical stimulation to achieve seizure control. In contrast to current closed-loop systems (RNS), which wait for the seizure to start before delivering stimulation, the BIC system will monitor the spatial topography and rate of stereotyped HFOs and deliver targeted stimulation to these HFO generating areas to prevent seizures from occurring. If the outcomes of our research in an acute setting become successful, the investigators will execute a clinical trial and run the developed methods with the implantable BIC system in a chronic ambulatory setting.
Primary Outcome
Outcome-2 will test the feasibility of capturing stereotyped HFO (sHFO) with the BIC system in the EMU setting. Once the feasibility of robust data transmission as listed in (Outcome-1) is tested, the neural activity will be recorded over 24 hours using the BIC system from 10 patients. The hardware will not be implanted but used externally to record the neural data. Then, the research team will compare whether the sHFO detection and SOZ localization accuracy is significantly different between th
Interventions
- DEVICE Brain Interchange System
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2026-07-01 |
| Est. Completion | 2029-08-31 |
| Phase | NA |
What is known before NCT06898138 opens enrollment
NCT06898138 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Brain Interchange System is the first listed.
NCT06898138 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06898138 about?
NCT06898138 is a clinical study titled "Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations". Overall, this study will investigate the functional utility of stereotyped HFOs by capturing them with a new implantable system (Brain Interchange - BIC of CorTec), which can sample neural data at higher rates \>=1kHz and deliver targeted electrical stimulation to achieve seizure control. In contras...
What is the current status of trial NCT06898138?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 8 participants. The study started on 2026-07-01. Estimated completion is 2029-08-31.
What interventions are being tested in trial NCT06898138?
The interventions under investigation include: Brain Interchange System (DEVICE).
Who is sponsoring clinical trial NCT06898138?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06898138's enrollment target sits among peer trials
8 1976th of 2000 higher than 19 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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