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NCT06892704 · ClinicalTrials.gov registry record
Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients.
A clinical trial of Smell Loss and Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP), sponsored by Northwestern University.
- Recruiting
- Registry status
- 30
- Enrollment target
- 1
- Study location
NCT06892704 is a study of Smell Loss and Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP) that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 30 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06892704, a study of Smell Loss and Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP), is actively recruiting participants, sponsored by Northwestern University.
- RECRUITING
- Registry status
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational study is to learn what can predict the return of the sense of smell in patients with chronic rhinosinusitis with nasal polyps being treated with dupilumab. The main questions it aims to answer are: 1. Does obstruction of the olfactory cleft predict return of the sense of smell? 2. Do electrophysiological signals generated by breathing and sniffing behavior predict return of the sense of smell? Participants starting dupilumab will undergo assessment for their degree of olfactory cleft obstruction, and an electrophysiologic assessment of their olfactory cleft and be followed over 6 months of treatment with dupilumab.
Conditions Studied
Interventions
- DRUG Dupilumab - Standard Dose
Study Locations (1)
Illinois
- Northwestern University Feinberg School of Medicine - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-05-01 |
| Est. Completion | 2027-12-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06892704
The ClinicalTrials.gov registry entry for NCT06892704 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Smell Loss appearing as the primary indexed condition, and to 1 intervention - of which Dupilumab - Standard Dose is the first listed.
NCT06892704 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT06892704 about?
NCT06892704 is a clinical study titled "Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients.". The goal of this observational study is to learn what can predict the return of the sense of smell in patients with chronic rhinosinusitis with nasal polyps being treated with dupilumab. The main questions it aims to answer are: 1. Does obstruction of the olfactory cleft predict return of the sense...
What is the current status of trial NCT06892704?
This trial is currently recruiting. The enrollment target is 30 participants. The study started on 2025-05-01. Estimated completion is 2027-12-31.
What conditions does trial NCT06892704 study?
This clinical trial studies the following conditions: Smell Loss, Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP).
What interventions are being tested in trial NCT06892704?
The interventions under investigation include: Dupilumab - Standard Dose (DRUG).
Who is sponsoring clinical trial NCT06892704?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06892704 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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