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NCT06138873 · ClinicalTrials.gov registry record · NA
Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy
A NA study of Ventricular Tachycardia and Ischemic Cardiomyopathy, sponsored by Rush University Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 5
- Study locations
NCT06138873 is a NA study of Ventricular Tachycardia and Ischemic Cardiomyopathy that is actively recruiting participants, run by Rush University Medical Center. The registered enrollment target is 100 participants, below the 285-participant average among 28 other Ventricular Tachycardia trials with a reported enrollment target (65% lower). The trial reports 5 study locations across 5 states.
The verdict
NCT06138873, a NA study of Ventricular Tachycardia and Ischemic Cardiomyopathy, is actively recruiting participants, sponsored by Rush University Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 5
- Study locations
Study Summary
Over the last decade, radiofrequency catheter ablation (RFCA) has become an established treatment for ventricular arrhythmias (VA). Due to the challenging nature of visualizing lesion formation in real time and ensuring an effective transmural lesion, different surrogate measures of lesion quality have been used. The Ablation Index (AI) is a variable incorporating power delivery in its formula and combining it with CF and time in a weighted equation which aims at allowing for a more precise estimation of lesion depth and quality when ablating VAs. AI guidance has previously been shown to improve outcomes in atrial and ventricular ablation in patients with premature ventricular complexes (PVC). However research on outcomes following AI-guidance for VT ablation specifically in patients with structural disease and prior myocardial infarction remains sparse. The investigators aim at conducting the first randomized controlled trial testing for the superiority of an AI-guided approach regarding procedural duration.
Conditions Studied
Interventions
- PROCEDURE Ablation-index guided ventricular tachycardia ablation
- PROCEDURE Ventricular tachycardia ablation with no AI-guidance
Study Locations (5)
Illinois
- Rush University Medical Center - Chicago
Massachusetts
- Mass General Brigham and Women's Hospital - Boston
Michigan
- Medical University of Michigan - Ann Arbor
Minnesota
- Mayo Clinic - Rochester
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2024-10-23 |
| Est. Completion | 2027-11-23 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06138873
The ClinicalTrials.gov registry entry for NCT06138873 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 285-participant average among 28 other Ventricular Tachycardia trials with a reported enrollment target (65% lower). The listed sponsor is Rush University Medical Center, which has 320 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Ventricular Tachycardia appearing as the primary indexed condition, and to 2 interventions - of which Ablation-index guided ventricular tachycardia ablation is the first listed.
NCT06138873 reports 5 study locations spanning 5 distinct geographic areas - top geographies include Illinois, Massachusetts, Michigan.
Frequently Asked Questions
What is clinical trial NCT06138873 about?
NCT06138873 is a clinical study titled "Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy". Over the last decade, radiofrequency catheter ablation (RFCA) has become an established treatment for ventricular arrhythmias (VA). Due to the challenging nature of visualizing lesion formation in real time and ensuring an effective transmural lesion, different surrogate measures of lesion quality h...
What is the current status of trial NCT06138873?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2024-10-23. Estimated completion is 2027-11-23.
What conditions does trial NCT06138873 study?
This clinical trial studies the following conditions: Ventricular Tachycardia, Ischemic Cardiomyopathy.
What interventions are being tested in trial NCT06138873?
The interventions under investigation include: Ablation-index guided ventricular tachycardia ablation (PROCEDURE), Ventricular tachycardia ablation with no AI-guidance (PROCEDURE).
Who is sponsoring clinical trial NCT06138873?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06138873 being conducted?
This trial has 5 study locations across Illinois, Massachusetts, Michigan, Minnesota, South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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