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ACTIVE NOT RECRUITING Phase 3

C-BEYOND: Efficacy and Safety of BEM/RZR vs. SOF/VEL in Subjects With Chronic HCV

NCT06868264 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to compare the efficacy and safety of BEM/RZR to SOF/VEL in adults with chronic HCV.

Interventions

  • DRUG Bemnifosbuvir-Ruzasvir (BEM/RZR)
  • DRUG Sofosbuvir-Velpatasvir (SOF/VEL)

Study Locations (20)

California

  • Atea Study Site — Bakersfield
  • Atea Study Site — Coronado
  • Atea Study Site — Escondido
  • Atea Study Site — Fresno
  • Atea Study Site — Long Beach
  • Atea Study Site — Los Angeles
  • Atea Study Site — Los Angeles
  • Atea Study Site — Orange
  • Atea Study Site — Pasadena
  • Atea Study Site — Sacramento
  • Atea Study Site — Torrance

Arizona

  • Atea Study Site — Chandler
  • Atea Study Site — Flagstaff
  • Atea Study Site — Mesa
  • Atea Study Site — Phoenix
  • Atea Study Site — Phoenix
  • Atea Study Site — Tucson

Alabama

  • Atea Study Site — Birmingham
  • Atea Study Site — Dothan

Arkansas

  • Atea Study Site — Little Rock

Trial Details

FieldValue
Enrollment Target 880 participants
Start Date 2025-04-07
Est. Completion 2026-12
Phase Phase 3

Sponsor

Atea Pharmaceuticals

36 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06868264

The ClinicalTrials.gov registry entry for NCT06868264 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 880 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Atea Pharmaceuticals, which has 36 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with HEPATITIS C VIRUS CHRONIC INFECTION appearing as the primary indexed condition, and to 2 interventions — of which Bemnifosbuvir-Ruzasvir (BEM/RZR) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06868264 reports 20 study locations spanning 4 distinct geographic areas — top geographies include California, Arizona, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06868264 about?

NCT06868264 is a clinical study titled "C-BEYOND: Efficacy and Safety of BEM/RZR vs. SOF/VEL in Subjects With Chronic HCV". The purpose of this study is to compare the efficacy and safety of BEM/RZR to SOF/VEL in adults with chronic HCV.

What is the current status of trial NCT06868264?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 880 participants. The study started on 2025-04-07. Estimated completion is 2026-12.

What conditions does trial NCT06868264 study?

This clinical trial studies the following conditions: HEPATITIS C VIRUS CHRONIC INFECTION. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06868264?

The interventions under investigation include: Bemnifosbuvir-Ruzasvir (BEM/RZR) (DRUG), Sofosbuvir-Velpatasvir (SOF/VEL) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06868264?

This trial is sponsored by Atea Pharmaceuticals, which has 36 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06868264 being conducted?

This trial has 20 study locations across Alabama, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial