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NCT06865170 · ClinicalTrials.gov registry record · Phase 4
Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?
A Phase 4 study, sponsored by University of California, Davis.
- Not yet
- Registry status
- Phase 4
- Development phase
- 88
- Enrollment target
NCT06865170 is a Phase 4 study that has not yet begun recruiting, run by University of California, Davis. The registered enrollment target is 88 participants.
The verdict
NCT06865170, a Phase 4 study, has not yet begun recruiting, sponsored by University of California, Davis.
- NOT YET RECRUITING
- Registry status
- Phase 4
- Development phase
- 88 participants
- Enrollment target
Study Summary
This study aims to investigate factors that affect the subjective experience of pain during and after intra-articular knee joint injection of steroids by comparing needle gauge size (22 G vs 25 G needles), as well as the presence or absence of topical ethyl chloride spray. Additionally, this study will investigate the effects of other various factors on patients' pain associated with the injection. Lastly, this study aims to determine the effect of patients' subjective pain from the injection on long-term clinical outcomes. Specific aims are as follows: Aim 1): Determine the effect of needle gauge size on patient reported pain associated with an ultrasound-guided intra-articular knee injection. Aim 2): Determine the effect of ethyl chloride spray on patient reported pain associated with an ultrasound-guided intra-articular knee injection. Aim 3): Determine the effect of sex, age, BMI, thigh size, severity of OA, and fear of needles on patient pain associated with an ultrasound-guided intra-articular knee injection. Aim 4) Determine the effect of patient pain from the procedure on longer term clinical outcomes after an ultrasound-guided intra-articular knee steroid injection. Researchers will obtain data at various time points, including pre-procedural data, immediately after the procedure, 24-48 hours after, and 6 weeks post-procedure. Participants will: Consent to receiving an intra-articular knee joint injection with steroids if indicated. Score their "procedural" pain immediately following the procedure, score their post-procedural "soreness" 24-48 hours after via telephone call, and score their overall knee pain about 6 weeks after the procedure via telephone call.
Interventions
- PROCEDURE 25 gauge needle
- PROCEDURE 22 gauge needle
- PROCEDURE +/- Ethyl Chloride Topical Aerosol Anesthetic
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2026-08 |
| Est. Completion | 2026-12 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06865170
The ClinicalTrials.gov registry entry for NCT06865170 describes a study currently listed as not yet recruiting, categorized as Phase 4. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which 25 gauge needle is the first listed.
NCT06865170 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06865170 about?
NCT06865170 is a clinical study titled "Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?". This study aims to investigate factors that affect the subjective experience of pain during and after intra-articular knee joint injection of steroids by comparing needle gauge size (22 G vs 25 G needles), as well as the presence or absence of topical ethyl chloride spray. Additionally, this study w...
What is the current status of trial NCT06865170?
This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 88 participants. The study started on 2026-08. Estimated completion is 2026-12.
What interventions are being tested in trial NCT06865170?
The interventions under investigation include: 25 gauge needle (PROCEDURE), 22 gauge needle (PROCEDURE), +/- Ethyl Chloride Topical Aerosol Anesthetic (PROCEDURE).
Who is sponsoring clinical trial NCT06865170?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
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