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NCT06858839 · ClinicalTrials.gov registry record · Phase 3
Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight
A Phase 3 study of Obesity, sponsored by Amgen.
- Active
- Registry status
- Phase 3
- Development phase
- 3,853
- Enrollment target
- 20
- Study locations
NCT06858839 is a Phase 3 study of Obesity that is active but no longer recruiting, run by Amgen. The registered enrollment target is 3,853 participants, above the 815-participant average among 1,053 other Obesity trials with a reported enrollment target (373% higher). The trial reports 20 study locations across 5 states.
The verdict
NCT06858839, a Phase 3 study of Obesity, is active but no longer recruiting, sponsored by Amgen.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 3,853 participants
- Enrollment target
- 20
- Study locations
Study Summary
The primary objective of this study is to demonstrate that maridebart cafraglutide is superior to placebo for percent change in body weight.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Maridebart Cafraglutide
Study Locations (20)
California
- Ark Clinical Research- Tustin - Fountain Valley
- Long Beach Clinical Trials Services Inc - Long Beach
- Ark Clinical Research- Long Beach - Long Beach
- Catalina Research Institute - Montclair
- Artemis Institute for Clinical Research - Riverside
- Artemis Institute for Clinical Research - San Diego
- Apex Clinical Research - San Diego
- Southern California Clinical Research - Santa Ana
- Diablo Clinical Research - Walnut Creek
Florida
- Indago Research and Health Center - Hialeah
- Jacksonville Center for Clinical Research - Jacksonville
- Clinical Neuroscience Solutions - Jacksonville - Jacksonville
- South Florida Wellness and Clinical Research Institute - Margate
- Optimus U Corporation - Miami
Alabama
- Pinnacle Research Group LLC - Anniston
- Alliance For Multispecialty Research - Daphne - Daphne
- Alliance for Multispecialty Research Mobile - Mobile
Connecticut
- Yale School of Medicine - New Haven
- Chase Medical Research LLC - Waterbury
Arizona
- Avacare Foothills Research Center - Phoenix
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,853 participants |
| Start Date | 2025-03-12 |
| Est. Completion | 2027-04-16 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06858839
The ClinicalTrials.gov registry entry for NCT06858839 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 3,853 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 815-participant average among 1,053 other Obesity trials with a reported enrollment target (373% higher). The listed sponsor is Amgen, which has 558 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06858839 reports 20 study locations spanning 5 distinct geographic areas - top geographies include California, Florida, Alabama.
Frequently Asked Questions
What is clinical trial NCT06858839 about?
NCT06858839 is a clinical study titled "Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight". The primary objective of this study is to demonstrate that maridebart cafraglutide is superior to placebo for percent change in body weight.
What is the current status of trial NCT06858839?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 3,853 participants. The study started on 2025-03-12. Estimated completion is 2027-04-16.
What conditions does trial NCT06858839 study?
This clinical trial studies the following conditions: Obesity.
What interventions are being tested in trial NCT06858839?
The interventions under investigation include: Placebo (DRUG), Maridebart Cafraglutide (DRUG).
Who is sponsoring clinical trial NCT06858839?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06858839 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.