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NCT06854406 · ClinicalTrials.gov registry record · Phase 1
A Study of Varenicline in the Treatment of Visceral Sensation
A Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 8
- Enrollment target
NCT06854406: Completed Phase 1 study, sponsored by Mayo Clinic.
NCT06854406 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 8 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06854406, a Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 8 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the effect of varenicline on rectal sensation, based on ascending method of limits and on graded rapid phasic distensions in participants with non-constipation IBS and chronic abdominal pain.
Primary Outcome
Pressure-volume relationship of rectum during balloon distension
Interventions
- DRUG Varenicline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2025-06-01 |
| Est. Completion | 2025-12-31 |
| Phase | Phase 1 |
What the finished NCT06854406 record still lists
NCT06854406 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 1 intervention - of which Varenicline is the first listed.
NCT06854406 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06854406 about?
NCT06854406 is a clinical study titled "A Study of Varenicline in the Treatment of Visceral Sensation". The purpose of this study is to evaluate the effect of varenicline on rectal sensation, based on ascending method of limits and on graded rapid phasic distensions in participants with non-constipation IBS and chronic abdominal pain.
What is the current status of trial NCT06854406?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2025-06-01. Estimated completion is 2025-12-31.
What interventions are being tested in trial NCT06854406?
The interventions under investigation include: Varenicline (DRUG).
Who is sponsoring clinical trial NCT06854406?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06854406's enrollment target sits among peer trials
8 1959th of 2000 higher than 29 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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