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NCT06811233 · ClinicalTrials.gov registry record · Phase 2

Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study

A Phase 2 study of Acute Myeloid Leukemia (AML), sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
140
Enrollment target
1
Study location

NCT06811233 is a Phase 2 study of Acute Myeloid Leukemia (AML) that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 140 participants, roughly in line with the 141-participant average among 29 other Acute Myeloid Leukemia (AML) trials with a reported enrollment target. The trial reports 1 study location across 1 state.

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The verdict

NCT06811233, a Phase 2 study of Acute Myeloid Leukemia (AML), is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
140 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical research study is to learn if metal detoxification (with calcium disodium edetate \[Ca-EDTA\] and dimercaptosuccinic acid \[DMSA\]) during standard therapy can help improve outcomes in patients with intermediate-risk, high-risk, or secondary AML compared to standard therapy alone. Researchers think lowering the level of metals found in the blood/bone marrow may help to control the disease and/or improve the response to chemotherapy.

Interventions

  • DRUG Magnesium Sulfate
  • DRUG DMSA
  • DRUG Ca-EDTA
  • DRUG Multivitamin

Study Locations (1)

Texas

  • The University of Texas M. D. Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 140 participants
Start Date 2025-05-08
Est. Completion 2031-08-31
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT06811233

The ClinicalTrials.gov registry entry for NCT06811233 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 140 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 141-participant average among 29 other Acute Myeloid Leukemia (AML) trials with a reported enrollment target. The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Acute Myeloid Leukemia (AML) appearing as the primary indexed condition, and to 4 interventions - of which Magnesium Sulfate is the first listed.

NCT06811233 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT06811233 about?

NCT06811233 is a clinical study titled "Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study". The goal of this clinical research study is to learn if metal detoxification (with calcium disodium edetate \[Ca-EDTA\] and dimercaptosuccinic acid \[DMSA\]) during standard therapy can help improve outcomes in patients with intermediate-risk, high-risk, or secondary AML compared to standard therapy...

What is the current status of trial NCT06811233?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 140 participants. The study started on 2025-05-08. Estimated completion is 2031-08-31.

What conditions does trial NCT06811233 study?

This clinical trial studies the following conditions: Acute Myeloid Leukemia (AML).

What interventions are being tested in trial NCT06811233?

The interventions under investigation include: Magnesium Sulfate (DRUG), DMSA (DRUG), Ca-EDTA (DRUG), Multivitamin (DRUG).

Who is sponsoring clinical trial NCT06811233?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06811233 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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