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NCT06788912 · ClinicalTrials.gov registry record · Phase 2
Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)
A Phase 2 study of Lung Neoplasm Malignant, sponsored by Merck Sharp & Dohme.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 20
- Study locations
NCT06788912 is a Phase 2 study of Lung Neoplasm Malignant that is actively recruiting participants, run by Merck Sharp & Dohme. The registered enrollment target is 60 participants. The trial reports 20 study locations across 13 states.
The verdict
NCT06788912, a Phase 2 study of Lung Neoplasm Malignant, is actively recruiting participants, sponsored by Merck Sharp & Dohme.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 20
- Study locations
Study Summary
The main goals are after treatment given before surgery, to measure the number of people who have no signs of cancer cells in tumors and lymph nodes removed during surgery; and to learn about whether the cancer gets smaller or goes away by measuring the number of people with a certain number of living cancer cells in the tumor removed during surgery.
Conditions Studied
Interventions
- DRUG Cisplatin
- DRUG Pemetrexed
- DRUG Gemcitabine
- DRUG Sacituzumab tirumotecan
- BIOLOGICAL Pembrolizumab (neoadjuvant)
Study Locations (20)
Other
- Országos Korányi Pulmonológiai Intézet ( Site 0060) - Budapest
- Ospedale San Raffaele. ( Site 0171) - Milan
- Fondazione IRCCS Istituto Nazionale dei Tumori ( Site 0175) - Milan
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 0174) - Roma
Region M. de Santiago
- Centro de Estudios Clínicos SAGA ( Site 0162) - Santiago
- FALP ( Site 0161) - Santiago
- Bradfordhill ( Site 0160) - Santiago
Attica
- Alexandra General Hospital of Athens Oncology-Hematology Unit ( Site 0203) - Athens
- ATTIKON GENERAL UNIVERSITY HOSPITAL-Oncology ( Site 0202) - Athens
- Metropolitan Hospital-4th Oncology Dept ( Site 0201) - Athens
Alabama
- Southern Cancer Center (SCC) ( Site 8004) - Daphne
California
- Sansum Clinic (Ridley Tree) ( Site 8012) - Santa Barbara
Maryland
- MedStar Franklin Square Medical Center ( Site 0033) - Baltimore
Oregon
- Oncology Associates of Oregon, P.C.(Willamette Valley Cancer Institute) (WVCI) ( Site 8006) - Eugene
Virginia
- Virginia Cancer Specialists (VCS) ( Site 8002) - Fairfax
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-03-20 |
| Est. Completion | 2032-02-06 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06788912
The ClinicalTrials.gov registry entry for NCT06788912 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Merck Sharp & Dohme, which has 558 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Lung Neoplasm Malignant appearing as the primary indexed condition, and to 5 interventions - of which Cisplatin is the first listed.
NCT06788912 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Other, Region M. de Santiago, Attica.
Frequently Asked Questions
What is clinical trial NCT06788912 about?
NCT06788912 is a clinical study titled "Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)". The main goals are after treatment given before surgery, to measure the number of people who have no signs of cancer cells in tumors and lymph nodes removed during surgery; and to learn about whether the cancer gets smaller or goes away by measuring the number of people with a certain number of livi...
What is the current status of trial NCT06788912?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2025-03-20. Estimated completion is 2032-02-06.
What conditions does trial NCT06788912 study?
This clinical trial studies the following conditions: Lung Neoplasm Malignant.
What interventions are being tested in trial NCT06788912?
The interventions under investigation include: Cisplatin (DRUG), Pemetrexed (DRUG), Gemcitabine (DRUG), Sacituzumab tirumotecan (DRUG), Pembrolizumab (neoadjuvant) (BIOLOGICAL).
Who is sponsoring clinical trial NCT06788912?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06788912 being conducted?
This trial has 20 study locations across Alabama, California, Maryland, Oregon, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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