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NCT06079970 · ClinicalTrials.gov registry record · NA

Confocal Laser Endomicroscopy VERification

A NA study of Lung Cancer and Carcinoma, Non-Small Cell Lung, sponsored by Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC).

Recruiting
Registry status
NA
Development phase
208
Enrollment target
7
Study locations

NCT06079970 is a NA study of Lung Cancer and Carcinoma, Non-Small Cell Lung that is actively recruiting participants, run by Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC). The registered enrollment target is 208 participants, below the 935-participant average among 409 other Lung Cancer trials with a reported enrollment target (78% lower). The trial reports 7 study locations across 2 states.

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The verdict

NCT06079970, a NA study of Lung Cancer and Carcinoma, Non-Small Cell Lung, is actively recruiting participants, sponsored by Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC).

RECRUITING
Registry status
NA
Development phase
208 participants
Enrollment target
7
Study locations

Study Summary

The goal of this multi-center randomized clinical trial is to evaluate the added value of needle based confocal laser endomicroscopy (nCLE)-imaging to regular diagnostic bronchoscopic peripheral lung lesion analysis on the diagnostic yield in patients with peripheral pulmonary nodules suspect for malignancy. The main question\[s\] it aims to answer are: To determine if the addition of nCLE-imaging to conventional diagnostic bronchoscopic peripheral lung lesion analysis results in an improved diagnostic yield (defined as the proportion of patients in whom the bronchoscopic procedure results in a definitive diagnosis out of the total number of patients that have received the diagnostic bronchoscopic procedure). Participants will undergo diagnostic bronchoscopy either with or without the addition of nCLE imaging before each TBNA. Based on the feedback of the CLE images on (in)correct placement of the needle, the needle might be repositioned before sampling. Comparison between the diagnostic yield of these groups will be done including subgroup analysis.

Interventions

  • DEVICE Neelde Based Confocal Laser Endomicroscopy
  • PROCEDURE Conventional diagnostic bronchoscopy

Study Locations (7)

Other

  • Vienna General Hospital - Vienna
  • General University Hospital Prague - Prague
  • Sotiria Hospital - Athens
  • Morgagni Pierantoni Hospital - Forlì
  • Amsterdam University Medical Centers - Amsterdam
  • University Hospital basel - Basel

New York

  • Montefiore Medical Center - New York

Trial Details

FieldValue
Enrollment Target 208 participants
Start Date 2023-10-18
Est. Completion 2025-10-18
Phase NA

What the Registry Record Tells You About NCT06079970

The ClinicalTrials.gov registry entry for NCT06079970 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 208 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 935-participant average among 409 other Lung Cancer trials with a reported enrollment target (78% lower). The listed sponsor is Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC), which has 1 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Lung Cancer appearing as the primary indexed condition, and to 2 interventions - of which Neelde Based Confocal Laser Endomicroscopy is the first listed.

NCT06079970 reports 7 study locations spanning 2 distinct geographic areas - top geographies include Other, New York.

Frequently Asked Questions

What is clinical trial NCT06079970 about?

NCT06079970 is a clinical study titled "Confocal Laser Endomicroscopy VERification". The goal of this multi-center randomized clinical trial is to evaluate the added value of needle based confocal laser endomicroscopy (nCLE)-imaging to regular diagnostic bronchoscopic peripheral lung lesion analysis on the diagnostic yield in patients with peripheral pulmonary nodules suspect for ma...

What is the current status of trial NCT06079970?

This trial is currently recruiting. It is a NA study. The enrollment target is 208 participants. The study started on 2023-10-18. Estimated completion is 2025-10-18.

What conditions does trial NCT06079970 study?

This clinical trial studies the following conditions: Lung Cancer, Carcinoma, Non-Small Cell Lung, Lung Neoplasm Malignant, Neoplasm of Lung.

What interventions are being tested in trial NCT06079970?

The interventions under investigation include: Neelde Based Confocal Laser Endomicroscopy (DEVICE), Conventional diagnostic bronchoscopy (PROCEDURE).

Who is sponsoring clinical trial NCT06079970?

This trial is sponsored by Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC), which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06079970 being conducted?

This trial has 7 study locations across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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