Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06761170 · ClinicalTrials.gov registry record · Phase 2

Spray Cryotherapy for the Management of Benign Central Airway Stenosis (Cryo-BAS)

A Phase 2 study of Stenosis of Trachea, sponsored by Beth Israel Deaconess Medical Center.

Recruiting
Registry status
Phase 2
Development phase
50
Enrollment target
1
Study location

NCT06761170: Recruiting Phase 2 study of Stenosis of Trachea, sponsored by Beth Israel Deaconess Medical Center.

NCT06761170 is a Phase 2 study of Stenosis of Trachea that is actively recruiting participants, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 50 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06761170, a Phase 2 study of Stenosis of Trachea, is actively recruiting participants, sponsored by Beth Israel Deaconess Medical Center.

RECRUITING
Registry status
Phase 2
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to compare spray cryotherapy plus balloon dilatation versus current standard of Care (SoC - steroid injection, radial cuts and balloon dilatation) in patients with benign airway stenosis with simple stenosis. The main question\[s\] investigators aim to answer are: 1. What is the need for reintervention and time to reintervention in participants with benign airway stenosis with simple stenosis who receive spray cryotherapy plus balloon dilatation versus standard of care alone? 2. To evaluate patient experience, physiological, anatomical changes, health care utilization and safety of the SCT plus balloon dilatation versus standard of care alone. Researchers will compare spray cryotherapy plus balloon dilatation versus current standard of Care (SoC - steroid injection, radial cuts and balloon dilatation) in patients with benign airway stenosis with simple stenosis to see if it reduces the need of re intervention. Participants will surgery and receive one of the two interventions.

Primary Outcome

Number of patients that require new intervention for the benign airway stenosis.

Conditions Studied

Interventions

  • PROCEDURE Standard of Care (SOC)
  • PROCEDURE Spray cryo therapy

Study Locations (1)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2025-06-02
Est. Completion 2027-01-15
Phase Phase 2

What NCT06761170 shows while recruiting

NCT06761170 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower).

The record links to 1 condition, with Stenosis of Trachea appearing as the primary indexed condition, and to 2 interventions - of which Standard of Care (SOC) is the first listed.

NCT06761170 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT06761170 about?

NCT06761170 is a clinical study titled "Spray Cryotherapy for the Management of Benign Central Airway Stenosis (Cryo-BAS)". The goal of this clinical trial is to compare spray cryotherapy plus balloon dilatation versus current standard of Care (SoC - steroid injection, radial cuts and balloon dilatation) in patients with benign airway stenosis with simple stenosis. The main question\[s\] investigators aim to answer are: ...

What is the current status of trial NCT06761170?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2025-06-02. Estimated completion is 2027-01-15.

What conditions does trial NCT06761170 study?

This clinical trial studies the following conditions: Stenosis of Trachea.

What interventions are being tested in trial NCT06761170?

The interventions under investigation include: Standard of Care (SOC) (PROCEDURE), Spray cryo therapy (PROCEDURE).

Who is sponsoring clinical trial NCT06761170?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06761170 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT06761170's enrollment target sits among peer trials

50 1195th of 2000 higher than 740 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00200889 · 50 participants · Early Phase 1

    Mapping Auricular Vagus Nerve Circuitry

  • NCT00409435 · 50 participants · Phase 2

    A Study of Pyridostigmine in Postural Tachycardia Syndrome

  • NCT01202305 · 50 participants

    The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies

  • NCT01225913 · 50 participants · Phase 4

    Mechanism(s) of Airflow Limitation During Exacerbation of Asthma

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT06761170, the US trial registry maintained by the National Library of Medicine. NCT06761170 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.