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NCT06760481 · ClinicalTrials.gov registry record · Phase 1

Phase I/Ib Trial of TIraGolumab, AtEzolizumab, and RadScopal Radiation in Patients With Advanced Solid Malignancies (TIGER)

A Phase 1 study of Advanced Solid Malignancies, sponsored by M.D. Anderson Cancer Center.

Active
Registry status
Phase 1
Development phase
7
Enrollment target
1
Study location

NCT06760481 is a Phase 1 study of Advanced Solid Malignancies that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 7 participants, below the 244-participant average among 6 other Advanced Solid Malignancies trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06760481, a Phase 1 study of Advanced Solid Malignancies, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
7 participants
Enrollment target
1
Study location

Study Summary

An open-label, Phase I/Ib study investigating the safety and efficacy of tiragolumab + atezolizumab + RadScopal™ XRT in patients with metastatic solid malignancies.

Conditions Studied

Advanced Solid Malignancies

Interventions

  • DRUG Atezolizumab
  • RADIATION Radiation Therapy
  • DRUG Tiragolumab

Study Locations (1)

Texas

  • The University of Texas M. D. Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2025-04-13
Est. Completion 2030-09-15
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06760481

The ClinicalTrials.gov registry entry for NCT06760481 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 244-participant average among 6 other Advanced Solid Malignancies trials with a reported enrollment target (97% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Solid Malignancies appearing as the primary indexed condition, and to 3 interventions - of which Atezolizumab is the first listed.

NCT06760481 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT06760481 about?

NCT06760481 is a clinical study titled "Phase I/Ib Trial of TIraGolumab, AtEzolizumab, and RadScopal Radiation in Patients With Advanced Solid Malignancies (TIGER)". An open-label, Phase I/Ib study investigating the safety and efficacy of tiragolumab + atezolizumab + RadScopal™ XRT in patients with metastatic solid malignancies.

What is the current status of trial NCT06760481?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 2025-04-13. Estimated completion is 2030-09-15.

What conditions does trial NCT06760481 study?

This clinical trial studies the following conditions: Advanced Solid Malignancies.

What interventions are being tested in trial NCT06760481?

The interventions under investigation include: Atezolizumab (DRUG), Radiation Therapy (RADIATION), Tiragolumab (DRUG).

Who is sponsoring clinical trial NCT06760481?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06760481 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.