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NCT06747949 · ClinicalTrials.gov registry record · Phase 3
A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)
A Phase 3 study of Sjögren's Syndrome, sponsored by Amgen.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 844
- Enrollment target
- 20
- Study locations
NCT06747949: Recruiting Phase 3 study of Sjögren's Syndrome, sponsored by Amgen.
NCT06747949 is a Phase 3 study of Sjögren's Syndrome that is actively recruiting participants, run by Amgen. The registered enrollment target is 844 participants, above the 297-participant average among 4 other Sjögren's Syndrome trials with a reported enrollment target (184% higher). The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06747949, a Phase 3 study of Sjögren's Syndrome, is actively recruiting participants, sponsored by Amgen.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 844 participants
- Enrollment target
- 20
- Study locations
Study Summary
The primary objective of this study is to evaluate the long-term safety and tolerability of dazodalibep.
Primary Outcome
Includes treatment emergent serious adverse events (TESAEs) and adverse events of special interest (AESIs).
Conditions Studied
Interventions
- DRUG Dazodalibep
Study Locations (20)
Arizona
- Arizona Arthritis & Rheumatology Associates - Avondale - Avondale
- Arizona Arthritis and Rheumatology Associates - Flagstaff - 399 S Malpais Ln - Flagstaff
- Arizona Arthritis and Rheumatology Associates - Gilbert - 3645 S Rome St - Gilbert
- Arizona Arthritis and Rheumatology Associates - Glendale - 5681 W Beverly Ln - Glendale
- Arizona Arthritis and Rheumatology Associates - Tucson - 2001 W Orange Grove Rd - Tucson
Florida
- Bradenton Research Center Inc - Bradenton
- Clinical Research of West Florida Inc - Clearwater - Clearwater
- BayCare Medical Group Primary Care and Rheumatology - Tampa - Tampa
North Carolina
- Arthritis and Osteoporosis Consultants of The Carolinas - Charlotte - 1918 Randolph Rd - Charlotte
- Duke Early Phase Clinical Research Unit - PPDS - Durham
- Onsite Clinical Solutions, LLC - Salisbury - Salisbury
California
- Samy Metyas MD Inc - Covina
- UCSD Altman Clinical and Translational Research Institute Building - La Jolla
Ohio
- Arthritis & Osteoporosis Center of Southwest Ohio - Miamisburg - Miamisburg
- University of Toledo Medical Center - Toledo
Colorado
- Tekton Research, LLC - 2121 E Harmony Rd - PPDS - Fort Collins
Massachusetts
- Tufts University School of Dental Medicine - Boston
Michigan
- Shores Rheumatology - Saint Clair Shores
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 844 participants |
| Start Date | 2025-02-25 |
| Est. Completion | 2029-12-11 |
| Phase | Phase 3 |
What NCT06747949 shows while recruiting
NCT06747949 is an interventional study that assigns participants to a tested intervention. The registered 844 participants enrollment target is mid-sized for trials with a published cap, above the 297-participant average among 4 other Sjögren's Syndrome trials with a reported enrollment target (184% higher).
The record links to 1 condition, with Sjögren's Syndrome appearing as the primary indexed condition, and to 1 intervention - of which Dazodalibep is the first listed.
NCT06747949 names 20 study sites across 10 states, led by Arizona, Florida, North Carolina.
Frequently Asked Questions
What is clinical trial NCT06747949 about?
NCT06747949 is a clinical study titled "A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)". The primary objective of this study is to evaluate the long-term safety and tolerability of dazodalibep.
What is the current status of trial NCT06747949?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 844 participants. The study started on 2025-02-25. Estimated completion is 2029-12-11.
What conditions does trial NCT06747949 study?
This clinical trial studies the following conditions: Sjögren's Syndrome.
What interventions are being tested in trial NCT06747949?
The interventions under investigation include: Dazodalibep (DRUG).
Who is sponsoring clinical trial NCT06747949?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06747949 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Florida, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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