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ACTIVE NOT RECRUITING Phase 3

A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome

NCT05946941 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to assess the safety and efficacy of two doses of Deucravacitinib in adult participants with Active Sjögren's Syndrome.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG Deucravacitinib

Study Locations (20)

California

  • Local Institution - 0228 — Fullerton
  • Local Institution - 0222 — La Palma
  • Local Institution - 0218 — San Francisco
  • Local Institution - 0203 — Santa Monica

Florida

  • Local Institution - 0049 — Clearwater
  • Local Institution - 0226 — Cooper City
  • Local Institution - 0223 — Sarasota

Georgia

  • Local Institution - 0140 — Augusta
  • Local Institution - 0229 — Lawrenceville

Louisiana

  • Local Institution - 0017 — Baton Rouge
  • Local Institution - 0125 — Monroe

Colorado

  • Local Institution - 0067 — Denver

Illinois

  • Local Institution - 0174 — Skokie

Kansas

  • Local Institution - 0016 — Kansas City

Maryland

  • Local Institution - 0187 — Baltimore

Trial Details

FieldValue
Enrollment Target 774 participants
Start Date 2023-09-11
Est. Completion 2028-11-16
Phase Phase 3

Sponsor

Bristol-Myers Squibb

504 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05946941

The ClinicalTrials.gov registry entry for NCT05946941 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 774 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bristol-Myers Squibb, which has 504 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Sjögren's Syndrome appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05946941 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, Florida, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05946941 about?

NCT05946941 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome". The purpose of this study is to assess the safety and efficacy of two doses of Deucravacitinib in adult participants with Active Sjögren's Syndrome.

What is the current status of trial NCT05946941?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 774 participants. The study started on 2023-09-11. Estimated completion is 2028-11-16.

What conditions does trial NCT05946941 study?

This clinical trial studies the following conditions: Sjögren's Syndrome. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05946941?

The interventions under investigation include: Placebo (OTHER), Deucravacitinib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05946941?

This trial is sponsored by Bristol-Myers Squibb, which has 504 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05946941 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial