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NCT05946941 · ClinicalTrials.gov registry record · Phase 3

A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome

A Phase 3 study of Sjögren's Syndrome, sponsored by Bristol-Myers Squibb.

Active
Registry status
Phase 3
Development phase
774
Enrollment target
20
Study locations

NCT05946941: Active Phase 3 study of Sjögren's Syndrome, sponsored by Bristol-Myers Squibb.

NCT05946941 is a Phase 3 study of Sjögren's Syndrome that is active but no longer recruiting, run by Bristol-Myers Squibb. The registered enrollment target is 774 participants, above the 315-participant average among 4 other Sjögren's Syndrome trials with a reported enrollment target (146% higher). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05946941, a Phase 3 study of Sjögren's Syndrome, is active but no longer recruiting, sponsored by Bristol-Myers Squibb.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
774 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to assess the safety and efficacy of two doses of Deucravacitinib in adult participants with Active Sjögren's Syndrome.

Conditions Studied

Sjögren's Syndrome

Interventions

  • OTHER Placebo
  • DRUG Deucravacitinib

Study Locations (20)

California

  • Local Institution - 0228 - Fullerton
  • Local Institution - 0222 - La Palma
  • Local Institution - 0218 - San Francisco
  • Local Institution - 0203 - Santa Monica

Florida

  • Local Institution - 0049 - Clearwater
  • Local Institution - 0226 - Cooper City
  • Local Institution - 0223 - Sarasota

Georgia

  • Local Institution - 0140 - Augusta
  • Local Institution - 0229 - Lawrenceville

Louisiana

  • Local Institution - 0017 - Baton Rouge
  • Local Institution - 0125 - Monroe

Colorado

  • Local Institution - 0067 - Denver

Illinois

  • Local Institution - 0174 - Skokie

Kansas

  • Local Institution - 0016 - Kansas City

Maryland

  • Local Institution - 0187 - Baltimore

Trial Details

FieldValue
Enrollment Target 774 participants
Start Date 2023-09-11
Est. Completion 2028-11-16
Phase Phase 3
Bristol-Myers Squibb

1,025 total trials

What the registry record for NCT05946941 still lists

NCT05946941 is an interventional study that assigns participants to a tested intervention. The registered 774 participants enrollment target is mid-sized for trials with a published cap, above the 315-participant average among 4 other Sjögren's Syndrome trials with a reported enrollment target (146% higher).

The record links to 1 condition, with Sjögren's Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05946941 names 20 study sites across 13 states, led by California, Florida, Georgia.

Frequently Asked Questions

What is clinical trial NCT05946941 about?

NCT05946941 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome". The purpose of this study is to assess the safety and efficacy of two doses of Deucravacitinib in adult participants with Active Sjögren's Syndrome.

What is the current status of trial NCT05946941?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 774 participants. The study started on 2023-09-11. Estimated completion is 2028-11-16.

What conditions does trial NCT05946941 study?

This clinical trial studies the following conditions: Sjögren's Syndrome.

What interventions are being tested in trial NCT05946941?

The interventions under investigation include: Placebo (OTHER), Deucravacitinib (DRUG).

Who is sponsoring clinical trial NCT05946941?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05946941 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Related registry views

Source: ClinicalTrials.gov NCT05946941, the US trial registry maintained by the National Library of Medicine. NCT05946941 (mid enrollment · wide site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.