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NCT06740253 · ClinicalTrials.gov registry record · NA

Safety and Acceptability Study of a Placebo Antibody-Based Nonhormonal Contraceptive Intravaginal Ring

A NA study, sponsored by The University of Texas Medical Branch, Galveston.

Completed
Registry status
NA
Development phase
14
Enrollment target

NCT06740253: Completed NA study, sponsored by The University of Texas Medical Branch, Galveston.

NCT06740253 is a NA study that has completed, run by The University of Texas Medical Branch, Galveston. The registered enrollment target is 14 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06740253, a NA study, has completed, sponsored by The University of Texas Medical Branch, Galveston.

COMPLETED
Registry status
NA
Development phase
14 participants
Enrollment target

Study Summary

In order to deliver nonhormonal vaginal contraceptive using anti-sperm antibodies, a new vaginal ring design using a capsule-IVR will be utilized. Evaluating the safety and acceptability of this device early in the product development cycle is important, not only because device/formulation characteristics become increasingly difficult to alter as product is advanced into clinical trials, but also because user adherence can directly impact clinical trial outcomes.

Primary Outcome

Determined by AE's, including colposcopy findings, that are deemed to be product related during placebo IVR use.

Interventions

  • DEVICE Placebo intravaginal ring (IVR)

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2025-02-11
Est. Completion 2025-07-28
Phase NA

What the finished NCT06740253 record still lists

NCT06740253 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Placebo intravaginal ring (IVR) is the first listed.

NCT06740253 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06740253 about?

NCT06740253 is a clinical study titled "Safety and Acceptability Study of a Placebo Antibody-Based Nonhormonal Contraceptive Intravaginal Ring". In order to deliver nonhormonal vaginal contraceptive using anti-sperm antibodies, a new vaginal ring design using a capsule-IVR will be utilized. Evaluating the safety and acceptability of this device early in the product development cycle is important, not only because device/formulation character...

What is the current status of trial NCT06740253?

This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2025-02-11. Estimated completion is 2025-07-28.

What interventions are being tested in trial NCT06740253?

The interventions under investigation include: Placebo intravaginal ring (IVR) (DEVICE).

Who is sponsoring clinical trial NCT06740253?

This trial is sponsored by The University of Texas Medical Branch, Galveston, which has 203 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06740253's enrollment target sits among peer trials

14 1909th of 2000 higher than 90 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06740253, the US trial registry maintained by the National Library of Medicine. NCT06740253 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.