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NCT06736925 · ClinicalTrials.gov registry record · NA

Omega-3 Fatty Acids and Subconcussive Head Impacts

A NA study of Omega 3 Fatty Acids and Subconcussive Head Impact, sponsored by Indiana University.

Recruiting
Registry status
NA
Development phase
208
Enrollment target
1
Study location

NCT06736925: Recruiting NA study of Omega 3 Fatty Acids and Subconcussive Head Impact, sponsored by Indiana University.

NCT06736925 is a NA study of Omega 3 Fatty Acids and Subconcussive Head Impact that is actively recruiting participants, run by Indiana University. The registered enrollment target is 208 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06736925, a NA study of Omega 3 Fatty Acids and Subconcussive Head Impact, is actively recruiting participants, sponsored by Indiana University.

RECRUITING
Registry status
NA
Development phase
208 participants
Enrollment target
1
Study location

Study Summary

The purpose of the proposed double-blind, randomized placebo-controlled trial is to understand how supplementation with fish oil \[docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)\] promote brain health against soccer heading. The study involves taking DHA+EPA or placebo, questionnaires, blood draws, brain imaging, tests to evaluate heart function, and soccer headings.

Primary Outcome

The primary outcome analyses will be comparing group differences (group x time interactions) in blood biomarkers, specifically NF-L (neurofilament light, ), tau (picogram per milliliter), GFAP (glial fibrillary acidic protein; nanograms per milliliter), UCH-L1 (ubiquitin C-terminal hydrolase-L1; picograms per milliliter), and S100B (S100 calcium binding protein B; nanograms per milliliter). The aggregation of all blood biomarkers will provide a comprehensive overview of the biofluid profile of t

Interventions

  • DIETARY_SUPPLEMENT Omega-3 Fatty Acids (EPA plus DHA)
  • DIETARY_SUPPLEMENT Organic soybean oil
  • OTHER Soccer Heading Model

Study Locations (1)

Indiana

  • Indiana University School of Public Health - Bloomington

Trial Details

FieldValue
Enrollment Target 208 participants
Start Date 2025-02-28
Est. Completion 2029-05-31
Phase NA
Indiana University

890 total trials

What NCT06736925 shows while recruiting

NCT06736925 is an interventional study that assigns participants to a tested intervention. The registered 208 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (85% lower).

The record links to 2 conditions, with Omega 3 Fatty Acids appearing as the primary indexed condition, and to 3 interventions - of which Omega-3 Fatty Acids (EPA plus DHA) is the first listed.

NCT06736925 reports a single indexed study location in Indiana.

Frequently Asked Questions

What is clinical trial NCT06736925 about?

NCT06736925 is a clinical study titled "Omega-3 Fatty Acids and Subconcussive Head Impacts". The purpose of the proposed double-blind, randomized placebo-controlled trial is to understand how supplementation with fish oil \[docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)\] promote brain health against soccer heading. The study involves taking DHA+EPA or placebo, questionnaires, b...

What is the current status of trial NCT06736925?

This trial is currently recruiting. It is a NA study. The enrollment target is 208 participants. The study started on 2025-02-28. Estimated completion is 2029-05-31.

What conditions does trial NCT06736925 study?

This clinical trial studies the following conditions: Omega 3 Fatty Acids, Subconcussive Head Impact.

What interventions are being tested in trial NCT06736925?

The interventions under investigation include: Omega-3 Fatty Acids (EPA plus DHA) (DIETARY_SUPPLEMENT), Organic soybean oil (DIETARY_SUPPLEMENT), Soccer Heading Model (OTHER).

Who is sponsoring clinical trial NCT06736925?

This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06736925 being conducted?

This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Omega 3 Fatty Acids

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06736925's enrollment target sits among peer trials

208 496th of 2000 higher than 1,502 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06736925, the US trial registry maintained by the National Library of Medicine. NCT06736925 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.