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RECRUITING Phase 3

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

NCT06719141 · View on ClinicalTrials.gov ↗

Study Summary

This (DEEp OCEAN Study) is a double-blind, randomized, placebo-controlled, multicenter study to investigate the efficacy, safety, and tolerability of LP352 in the treatment of seizures in children and adults with DEE. The study consists of 3 main phases: Screening, Titration period, Maintenance period, followed by a Taper period and Follow-Up. The total duration of the study will be approximately 24 months.

Interventions

  • DRUG Placebo
  • DRUG LP352

Study Locations (20)

Florida

  • NW FL Clinical Research Group, LLC — Gulf Breeze
  • University of Miami - 1120 NW 14th St — Miami
  • Nicklaus Children's Hospital - PIN — Miami
  • Research Institute of Orlando LLC — Orlando
  • University of South Florida - 2 Tampa General Circle — Tampa
  • Pediatric Epilepsy and Neurology Specialists — Tampa

California

  • Children's Hospital Los Angeles - PIN — Los Angeles
  • David Geffen School of Medicine at UCLA — Los Angeles
  • The Stanford Division of Child Neurology — Palo Alto
  • UCSF Children's Hospital — San Francisco

Georgia

  • Children's Healthcare of Atlanta - Center for Advanced Pediatrics - PIN — Atlanta
  • Rare Disease Research, LLC - Atlanta - RDR - PIN — Atlanta

Arkansas

  • Arkansas Children's Hospital - PIN — Little Rock

Colorado

  • Children's Hospital Colorado. — Aurora

District of Columbia

  • Children's National Medical Center — Washington D.C.

Idaho

  • Consultants In Epilepsy and Neurology PLLC — Boise

Illinois

  • Ann and Robert H Lurie Childrens Hospital of Chicago - PIN — Chicago

Trial Details

FieldValue
Enrollment Target 320 participants
Start Date 2024-11-11
Est. Completion 2026-11-30
Phase Phase 3

Sponsor

Longboard Pharmaceuticals

4 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06719141

The ClinicalTrials.gov registry entry for NCT06719141 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 320 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Longboard Pharmaceuticals, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Developmental and Epileptic Encephalopathy appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06719141 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Florida, California, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06719141 about?

NCT06719141 is a clinical study titled "A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)". This (DEEp OCEAN Study) is a double-blind, randomized, placebo-controlled, multicenter study to investigate the efficacy, safety, and tolerability of LP352 in the treatment of seizures in children and adults with DEE. The study consists of 3 main phases: Screening, Titration period, Maintenance peri...

What is the current status of trial NCT06719141?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 320 participants. The study started on 2024-11-11. Estimated completion is 2026-11-30.

What conditions does trial NCT06719141 study?

This clinical trial studies the following conditions: Developmental and Epileptic Encephalopathy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06719141?

The interventions under investigation include: Placebo (DRUG), LP352 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06719141?

This trial is sponsored by Longboard Pharmaceuticals, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06719141 being conducted?

This trial has 20 study locations across Arkansas, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial