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NCT06690138 · ClinicalTrials.gov registry record · Phase 1
A Study to Determine the Effect of Itraconazole on the Pharmacokinetics of Divarasib in Healthy Participants
A Phase 1 study, sponsored by Genentech.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
NCT06690138: Completed Phase 1 study, sponsored by Genentech.
NCT06690138 is a Phase 1 study that has completed, run by Genentech. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06690138, a Phase 1 study, has completed, sponsored by Genentech.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
Study Summary
This is a Phase 1, open-label, two-period, fixed sequence drug-drug interaction study to evaluate the impact of multiple doses of Itraconazole on the pharmacokinetics (PK) and safety of Divarasib in healthy participants.
Interventions
- DRUG Divarasib
- DRUG Itraconazole
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2024-11-15 |
| Est. Completion | 2025-02-11 |
| Phase | Phase 1 |
What the finished NCT06690138 record still lists
NCT06690138 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 2 interventions - of which Divarasib is the first listed.
NCT06690138 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06690138 about?
NCT06690138 is a clinical study titled "A Study to Determine the Effect of Itraconazole on the Pharmacokinetics of Divarasib in Healthy Participants". This is a Phase 1, open-label, two-period, fixed sequence drug-drug interaction study to evaluate the impact of multiple doses of Itraconazole on the pharmacokinetics (PK) and safety of Divarasib in healthy participants.
What is the current status of trial NCT06690138?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2024-11-15. Estimated completion is 2025-02-11.
What interventions are being tested in trial NCT06690138?
The interventions under investigation include: Divarasib (DRUG), Itraconazole (DRUG).
Who is sponsoring clinical trial NCT06690138?
This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06690138's enrollment target sits among peer trials
18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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