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NCT06682299 · ClinicalTrials.gov registry record · NA
Maintenance TMS in Treatment Resistant Depression
A NA study of Treatment Resistant Depression (TRD), sponsored by Austin Messner.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT06682299 is a NA study of Treatment Resistant Depression (TRD) that is actively recruiting participants, run by Austin Messner. The registered enrollment target is 30 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06682299, a NA study of Treatment Resistant Depression (TRD), is actively recruiting participants, sponsored by Austin Messner.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Electroconvulsive therapy (ECT) is one of the most efficacious treatments available for treatment-resistant depression (TRD). Although a maintenance ECT protocol exists, multiple barriers limit its use for long-term use. These barriers include procedure tolerability, cognitive side effects, financial burden, and unreliable social support to accompany patients for these treatments. On the other hand, a different modality of noninvasive neuromodulation called transcranial magnetic stimulation (TMS) can be performed in the outpatient setting and does not need anesthesia. The likelihood of cognitive adverse effects with TMS is much lower than with ECT. Our clinical question encompasses piloting a maintenance TMS regimen to maintain remission in treatment-resistant major depressive disorder. This will be a patient-preference clinical trial, with patients offered the choice to initiate maintenance TMS versus maintenance ECT after their index ECT sessions for treatment-resistant depression. There will be no randomization or placebo involved in this study.
Conditions Studied
Interventions
- DEVICE Transmagnetic Stimulation
- DEVICE Electroconvulsive Therapy
Study Locations (1)
Kentucky
- University of Kentucky - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-04-17 |
| Est. Completion | 2026-04-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06682299
The ClinicalTrials.gov registry entry for NCT06682299 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Austin Messner, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Treatment Resistant Depression (TRD) appearing as the primary indexed condition, and to 2 interventions - of which Transmagnetic Stimulation is the first listed.
NCT06682299 reports 1 study location spanning 1 distinct geographic area - top geographies include Kentucky.
Frequently Asked Questions
What is clinical trial NCT06682299 about?
NCT06682299 is a clinical study titled "Maintenance TMS in Treatment Resistant Depression". Electroconvulsive therapy (ECT) is one of the most efficacious treatments available for treatment-resistant depression (TRD). Although a maintenance ECT protocol exists, multiple barriers limit its use for long-term use. These barriers include procedure tolerability, cognitive side effects, financia...
What is the current status of trial NCT06682299?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-04-17. Estimated completion is 2026-04-01.
What conditions does trial NCT06682299 study?
This clinical trial studies the following conditions: Treatment Resistant Depression (TRD).
What interventions are being tested in trial NCT06682299?
The interventions under investigation include: Transmagnetic Stimulation (DEVICE), Electroconvulsive Therapy (DEVICE).
Who is sponsoring clinical trial NCT06682299?
This trial is sponsored by Austin Messner, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06682299 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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