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NCT06678659 · ClinicalTrials.gov registry record · Phase 1
A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer
A Phase 1 study of Locally Advanced and Unresectable, sponsored by Recursion Pharmaceuticals.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 85
- Enrollment target
- 6
- Study locations
NCT06678659 is a Phase 1 study of Locally Advanced and Unresectable that is actively recruiting participants, run by Recursion Pharmaceuticals. The registered enrollment target is 85 participants, below the 163-participant average among 6 other Locally Advanced trials with a reported enrollment target (48% lower). The trial reports 6 study locations across 6 states.
The verdict
NCT06678659, a Phase 1 study of Locally Advanced and Unresectable, is actively recruiting participants, sponsored by Recursion Pharmaceuticals.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 85 participants
- Enrollment target
- 6
- Study locations
Study Summary
This is a multi-center, open-label study to investigate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary activity of REC-1245 administered orally on a once daily (QD) schedule in participants with unresectable, locally advanced, or metastatic solid tumors.
Conditions Studied
Interventions
- DRUG REC-1245
Study Locations (6)
California
- City of Hope - Duarte
Ohio
- Cleveland Clinic - Cleveland
Tennessee
- SCRI Oncology Partners - PPDS - Nashville
Utah
- START Mountain Region - West Valley City
Canada
- McGill University Health Centre (MUHC) - The Montreal - Québec
Ontario
- Princess Margaret Cancer Centre - Toronto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 85 participants |
| Start Date | 2024-11-21 |
| Est. Completion | 2028-10-30 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06678659
The ClinicalTrials.gov registry entry for NCT06678659 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 85 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 163-participant average among 6 other Locally Advanced trials with a reported enrollment target (48% lower). The listed sponsor is Recursion Pharmaceuticals, which has 6 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Locally Advanced appearing as the primary indexed condition, and to 1 intervention - of which REC-1245 is the first listed.
NCT06678659 reports 6 study locations spanning 6 distinct geographic areas - top geographies include California, Ohio, Tennessee.
Frequently Asked Questions
What is clinical trial NCT06678659 about?
NCT06678659 is a clinical study titled "A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer". This is a multi-center, open-label study to investigate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary activity of REC-1245 administered orally on a once daily (QD) schedule in participants with unresectable, locally advanced, or metastatic solid tumors.
What is the current status of trial NCT06678659?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 85 participants. The study started on 2024-11-21. Estimated completion is 2028-10-30.
What conditions does trial NCT06678659 study?
This clinical trial studies the following conditions: Locally Advanced, Unresectable, Metastatic Cancers, Relapsed/Refractory Lymphomas.
What interventions are being tested in trial NCT06678659?
The interventions under investigation include: REC-1245 (DRUG).
Who is sponsoring clinical trial NCT06678659?
This trial is sponsored by Recursion Pharmaceuticals, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06678659 being conducted?
This trial has 6 study locations across California, Ohio, Tennessee, Utah, Canada. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.