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NCT06676098 · ClinicalTrials.gov registry record · NA
The Optimal Injection Site for a 3D Guided Inferior Alveolar Nerve Block Device (IANBD)
A NA study of Inferior Alveolar Nerve Block, sponsored by Boston University.
- Recruiting
- Registry status
- NA
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT06676098 is a NA study of Inferior Alveolar Nerve Block that is actively recruiting participants, run by Boston University. The registered enrollment target is 10 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06676098, a NA study of Inferior Alveolar Nerve Block, is actively recruiting participants, sponsored by Boston University.
- RECRUITING
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
Given the thicker cortical bone in the mandible compared to the maxilla, mandibular teeth cannot be effectively anesthetized via local infiltration anesthesia. Instead, clinicians typically perform regional anesthesia and most commonly, Inferior Alveolar Nerve block (IANB). However, the inferior alveolar nerve is deeply submerged by surrounding structures of bone, muscles, ligaments and vessels. Traditional IANB is a technique by using anatomical landmarks not directly related to Inferior Alveolar Nerve (IAN) to approximate the location of mandibular foramen, where IAN enters mandible. IANB is considered a blind technique and known for the lack of accuracy and precision. The failure rate can be as high as 30-45%. In contrast, the investigator's cone beam computed tomography (CBCT) guided IANB device (IANBD) effectively directs the needle to the mandibular foramen which improves the success rate of the IANB on the first attempt, minimizes injection tissue damage, and reduces patient discomfort. In this proof of concept trial, a 3D printed CBCT guided IANBD will be used to administer anesthesia at three injection sites instead of the traditional IANB technique. Participants will be consented patients at the postdoctoral endodontic treatment center, Department of Endodontics, Boston University (BU) Henry M. Goldman School of Dentistry. The goal of this research is to to evaluate the acceptability, safety, and effectiveness of guided anesthesia using the IANBD by enrolling 10 subjects who require non-surgical endodontic therapy with a simple, affordable and reliable prototype to be used by clinicians in the dental care setting.
Conditions Studied
Interventions
- PROCEDURE IANBD 3D guided approach
Study Locations (1)
Massachusetts
- Goldman School of Dental Medicine, Boston University - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2025-12-17 |
| Est. Completion | 2027-11 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06676098
The ClinicalTrials.gov registry entry for NCT06676098 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boston University, which has 185 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Inferior Alveolar Nerve Block appearing as the primary indexed condition, and to 1 intervention - of which IANBD 3D guided approach is the first listed.
NCT06676098 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06676098 about?
NCT06676098 is a clinical study titled "The Optimal Injection Site for a 3D Guided Inferior Alveolar Nerve Block Device (IANBD)". Given the thicker cortical bone in the mandible compared to the maxilla, mandibular teeth cannot be effectively anesthetized via local infiltration anesthesia. Instead, clinicians typically perform regional anesthesia and most commonly, Inferior Alveolar Nerve block (IANB). However, the inferior alv...
What is the current status of trial NCT06676098?
This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2025-12-17. Estimated completion is 2027-11.
What conditions does trial NCT06676098 study?
This clinical trial studies the following conditions: Inferior Alveolar Nerve Block.
What interventions are being tested in trial NCT06676098?
The interventions under investigation include: IANBD 3D guided approach (PROCEDURE).
Who is sponsoring clinical trial NCT06676098?
This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06676098 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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