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NCT06669650 · ClinicalTrials.gov registry record · Phase 4
Personalized Post-Operative Pain Management
A Phase 4 study of Post-surgical Pain and Persistent Post Operative Opioid Use, sponsored by University of Tennessee Graduate School of Medicine.
- Active
- Registry status
- Phase 4
- Development phase
- 208
- Enrollment target
- 1
- Study location
NCT06669650 is a Phase 4 study of Post-surgical Pain and Persistent Post Operative Opioid Use that is active but no longer recruiting, run by University of Tennessee Graduate School of Medicine. The registered enrollment target is 208 participants, below the 276-participant average among 4 other Post-surgical Pain trials with a reported enrollment target (25% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06669650, a Phase 4 study of Post-surgical Pain and Persistent Post Operative Opioid Use, is active but no longer recruiting, sponsored by University of Tennessee Graduate School of Medicine.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 4
- Development phase
- 208 participants
- Enrollment target
- 1
- Study location
Study Summary
The main questions this study aims to answer are: Does perioperative PGx personalized opiate therapy reduce persistent post-operative opioid use dependency, improve pain management and reduce opiate related adverse events in opioid naïve patients after surgery? Participants will: Take hydromorphone if the PGx results determine they have a SNP indicating high or low metabolic activity in the CYP2D6 enzyme. Complete a 7-day pain diary post-discharge. Complete a follow-up phone call once per month for 90 days.
Conditions Studied
Interventions
- DRUG Oxycodone
- DRUG Hydromorphone
- OTHER PGx guided personalized post-operative pain management
Study Locations (1)
Tennessee
- The University of Tennessee Graduate School of Medicine - Knoxville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 208 participants |
| Start Date | 2024-09-25 |
| Est. Completion | 2025-12 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06669650
The ClinicalTrials.gov registry entry for NCT06669650 describes a study currently listed as active not recruiting, categorized as Phase 4. The registered enrollment target is 208 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 276-participant average among 4 other Post-surgical Pain trials with a reported enrollment target (25% lower). The listed sponsor is University of Tennessee Graduate School of Medicine, which has 20 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Post-surgical Pain appearing as the primary indexed condition, and to 3 interventions - of which Oxycodone is the first listed.
NCT06669650 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT06669650 about?
NCT06669650 is a clinical study titled "Personalized Post-Operative Pain Management". The main questions this study aims to answer are: Does perioperative PGx personalized opiate therapy reduce persistent post-operative opioid use dependency, improve pain management and reduce opiate related adverse events in opioid naïve patients after surgery? Participants will: Take hydromorpho...
What is the current status of trial NCT06669650?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 208 participants. The study started on 2024-09-25. Estimated completion is 2025-12.
What conditions does trial NCT06669650 study?
This clinical trial studies the following conditions: Post-surgical Pain, Persistent Post Operative Opioid Use.
What interventions are being tested in trial NCT06669650?
The interventions under investigation include: Oxycodone (DRUG), Hydromorphone (DRUG), PGx guided personalized post-operative pain management (OTHER).
Who is sponsoring clinical trial NCT06669650?
This trial is sponsored by University of Tennessee Graduate School of Medicine, which has 20 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06669650 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.