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NCT06667336 · ClinicalTrials.gov registry record · NA
The Impact of Suctioning on Oxygenation During RSI in the Emergency Department
A NA study, sponsored by Maimonides Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 76
- Enrollment target
NCT06667336: Completed NA study, sponsored by Maimonides Medical Center.
NCT06667336 is a NA study that has completed, run by Maimonides Medical Center. The registered enrollment target is 76 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06667336, a NA study, has completed, sponsored by Maimonides Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 76 participants
- Enrollment target
Study Summary
Rapid Sequence Intubation (RSI) is a common procedure in Emergency Departments (ED). However, it is a high-risk procedure and has been associated with significant complications including hypoxia, hypotension, airway trauma, aspiration, and death. Specifically, hypoxic episodes during intubation can lead to poor outcomes such as dysrhythmias, haemodynamic compromise, hypoxic brain injury and cardiac arrest, and is therefore of primary concern during any intubation procedure. Aspiration is a serious adverse event and potential cause of hypoxia during RSI and can lead to poor patient outcomes downstream of the procedure. The reported incidence of aspiration during RSI in the ED ranges from 3 to 8% in the ED population. In order to achieve an optimal view of the glottis and prevent pulmonary aspiration of fluids in the oropharynx, providers apply suction prior to and during laryngoscopy, using a Yankauer or large-bore suction catheter. There is currently significant variation in suctioning during laryngoscopy, with some providers using very little suction as needed to clear heavy fluids (judicious suctioning), while others utilise suction aggressively (lead with suction) and as a part of their routine laryngoscopy technique. Evidence suggests inline suction on already-intubated patients accelerates desaturation, but we are aware of no studies examining the impact suctioning has on the speed of desaturation during emergent endotracheal intubation. This pilot study aims to compare the effects of intermittent, as-needed "judicious" suctioning versus aggressive "continuous" (lead with) suctioning on oxygenation during rapid sequence intubation in the emergency department.
Primary Outcome
the oxygen saturation achieved (SpO2) at the time of tube placement (via confirmation with first ETCO2 waveform) achieved during the intubation period.
Interventions
- PROCEDURE intermittent suction
- PROCEDURE continuous suction
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2021-09-01 |
| Est. Completion | 2024-10-28 |
| Phase | NA |
What the finished NCT06667336 record still lists
NCT06667336 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which intermittent suction is the first listed.
NCT06667336 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06667336 about?
NCT06667336 is a clinical study titled "The Impact of Suctioning on Oxygenation During RSI in the Emergency Department". Rapid Sequence Intubation (RSI) is a common procedure in Emergency Departments (ED). However, it is a high-risk procedure and has been associated with significant complications including hypoxia, hypotension, airway trauma, aspiration, and death. Specifically, hypoxic episodes during intubation can ...
What is the current status of trial NCT06667336?
This trial is currently completed. It is a NA study. The enrollment target is 76 participants. The study started on 2021-09-01. Estimated completion is 2024-10-28.
What interventions are being tested in trial NCT06667336?
The interventions under investigation include: intermittent suction (PROCEDURE), continuous suction (PROCEDURE).
Who is sponsoring clinical trial NCT06667336?
This trial is sponsored by Maimonides Medical Center, which has 39 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06667336's enrollment target sits among peer trials
76 1062nd of 2000 higher than 932 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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