Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03511118 · ClinicalTrials.gov registry record

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

A clinical trial of Lactating Women on Select DOI and Breastfed Infants of Mothers on Select DOI, sponsored by Duke University.

Recruiting
Registry status
1,600
Enrollment target
20
Study locations

NCT03511118 is a study of Lactating Women on Select DOI and Breastfed Infants of Mothers on Select DOI that is actively recruiting participants, run by Duke University. The registered enrollment target is 1,600 participants. The trial reports 20 study locations across 12 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03511118, a study of Lactating Women on Select DOI and Breastfed Infants of Mothers on Select DOI, is actively recruiting participants, sponsored by Duke University.

RECRUITING
Registry status
1,600 participants
Enrollment target
20
Study locations

Study Summary

Over half of women in the US who are breastfeeding their infants take prescription drugs. You are being asked to participate in this study because you are breastfeeding your infant and are currently taking, as part of your medical care, at least one of the drugs we are studying. We are interested in studying drugs commonly prescribed to women who are breastfeeding so we can learn more about the amount of drug that is transferred to breastmilk and estimate how much of drug that is consumed by breastfed infants.

Interventions

  • DRUG Tranexamic acid (TXA)
  • DRUG labetalol
  • DRUG metformin
  • DRUG nifedipine
  • DRUG clindamycin

Study Locations (20)

Texas

  • Texas Tech University Health Sciences Center School of Medicine. - Amarillo
  • University of Texas Medical Branch - Galveston - Galveston
  • University of Texas Health Science Center at Houston - Houston
  • The Women's Hospital of Texas - Houston
  • University of Texas Health Science Center - San Antonio

California

  • University of California-San Diego Medical Center - La Jolla
  • Loma Linda University Health - Loma Linda

Illinois

  • Northwestern University - Chicago
  • Ann and Robert H. Lurie Childrens Hospital of Chicago - Chicago

North Carolina

  • University of North Carolina Hospital - Chapel Hill
  • Duke University Maternal and Fetal Medicine - Durham

Pennsylvania

  • Hospital of the University of Pennsylvania Department of Maternal Fetal Medicine - Philadelphia
  • University of Pittsburgh School of Medicine - Pittsburgh

Indiana

  • Indiana University Health - Indianapolis

Iowa

  • University of Iowa Hospitals and Clinics - Iowa City

Minnesota

  • Children's Hospital and Clinics - Minneapolis - Minneapolis

Trial Details

FieldValue
Enrollment Target 1,600 participants
Start Date 2018-10-04
Est. Completion 2027-07-31

Sponsor

Duke University

1,725 total trials

What the Registry Record Tells You About NCT03511118

The ClinicalTrials.gov registry entry for NCT03511118 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,600 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Lactating Women on Select DOI appearing as the primary indexed condition, and to 5 interventions - of which Tranexamic acid (TXA) is the first listed.

NCT03511118 reports 20 study locations spanning 12 distinct geographic areas - top geographies include Texas, California, Illinois.

Frequently Asked Questions

What is clinical trial NCT03511118 about?

NCT03511118 is a clinical study titled "Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants". Over half of women in the US who are breastfeeding their infants take prescription drugs. You are being asked to participate in this study because you are breastfeeding your infant and are currently taking, as part of your medical care, at least one of the drugs we are studying. We are interested in...

What is the current status of trial NCT03511118?

This trial is currently recruiting. The enrollment target is 1,600 participants. The study started on 2018-10-04. Estimated completion is 2027-07-31.

What conditions does trial NCT03511118 study?

This clinical trial studies the following conditions: Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI.

What interventions are being tested in trial NCT03511118?

The interventions under investigation include: Tranexamic acid (TXA) (DRUG), labetalol (DRUG), metformin (DRUG), nifedipine (DRUG), clindamycin (DRUG).

Who is sponsoring clinical trial NCT03511118?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03511118 being conducted?

This trial has 20 study locations across California, Illinois, Indiana, Iowa, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.