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NCT06649591 · ClinicalTrials.gov registry record
Expert Consensus and Artificial Intelligence in Medical Decision Making in Patients with Malignant Brain Tumors
A clinical trial of Malignant Brain Tumors, sponsored by Tufts Medical Center.
- Active
- Registry status
- 225
- Enrollment target
- 1
- Study location
NCT06649591: Active study of Malignant Brain Tumors, sponsored by Tufts Medical Center.
NCT06649591 is a study of Malignant Brain Tumors that is active but no longer recruiting, run by Tufts Medical Center. The registered enrollment target is 225 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06649591, a study of Malignant Brain Tumors, is active but no longer recruiting, sponsored by Tufts Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- 225 participants
- Enrollment target
- 1
- Study location
Study Summary
Nearly 23,000 adults are diagnosed with primary central nervous system (CNS) malignancy yearly. An additional 200,000 adults are diagnosed with brain metastasis. There are significant variations in CNS tumor treatment. However, due to significant heterogeneity in patient baseline factors, identifying unwarranted variation is challenging. Ghogawala et al have previously demonstrated that, among patients undergoing surgical treatment of cervical myelopathy and lumbar degenerative spinal disease, an expert panel consisting of surgeon experts can identify variations in proposed surgical procedure and demonstrated superior patient outcomes when the surgery performed matched the procedure recommended by expert consensus. Expert panel surveys have not previously been used to identify variations in care among patients with CNS malignancy. The primary aim is to determine whether patient outcomes are superior when treatment aligns with recommendations made by a clinical expert neurosurgical panel. The study also seek to identify patient factors that predispose to variability in care. Our long-term aim is to determine whether predictive artificial learning algorithms can achieve the same outcomes, or better, as clinical expert panels, but with greater efficiency and greater capacity to be available for more patients. The investigators hypothesize that: * When a team of 10 medical experts has greater than 80% consensus regarding optimal treatment and when the doctor and patient select that specific treatment, the outcome is superior than when a patient and doctor select an alternative procedure. * When a team of 10 medical experts has greater than 80% consensus regarding optimal treatment, the structured data used by the experts can be processed and trained by computing algorithms to predict the pattern recognized by the experts - i.e. - the computer can predict how an expert panel would vote. Procedures include the following: 1. Chart review portion of study: Patients will
Primary Outcome
Patients alive at last follow up through study completion, an average of 2 years
Conditions Studied
Interventions
- BEHAVIORAL Survey
Study Locations (1)
Massachusetts
- Tufts Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 225 participants |
| Start Date | 2017-07-01 |
| Est. Completion | 2025-12 |
What the registry record for NCT06649591 still lists
NCT06649591 is an observational study that tracks outcomes without assigning an intervention. The registered 225 participants enrollment target is mid-sized for trials with a published cap.
The record links to 1 condition, with Malignant Brain Tumors appearing as the primary indexed condition, and to 1 intervention - of which Survey is the first listed.
NCT06649591 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06649591 about?
NCT06649591 is a clinical study titled "Expert Consensus and Artificial Intelligence in Medical Decision Making in Patients with Malignant Brain Tumors". Nearly 23,000 adults are diagnosed with primary central nervous system (CNS) malignancy yearly. An additional 200,000 adults are diagnosed with brain metastasis. There are significant variations in CNS tumor treatment. However, due to significant heterogeneity in patient baseline factors, identifyin...
What is the current status of trial NCT06649591?
This trial is currently active not recruiting. The enrollment target is 225 participants. The study started on 2017-07-01. Estimated completion is 2025-12.
What conditions does trial NCT06649591 study?
This clinical trial studies the following conditions: Malignant Brain Tumors.
What interventions are being tested in trial NCT06649591?
The interventions under investigation include: Survey (BEHAVIORAL).
Who is sponsoring clinical trial NCT06649591?
This trial is sponsored by Tufts Medical Center, which has 169 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06649591 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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