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NCT06648824 · ClinicalTrials.gov registry record · Phase 1
Study of How Mitapivat Affects Midazolam Blood Levels in Healthy Participants
A Phase 1 study, sponsored by Agios Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT06648824: Completed Phase 1 study, sponsored by Agios Pharmaceuticals.
NCT06648824 is a Phase 1 study that has completed, run by Agios Pharmaceuticals. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06648824, a Phase 1 study, has completed, sponsored by Agios Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
The primary purpose of this study is to assess the effect of mitapivat on the single oral dose pharmacokinetics (PK) of midazolam in healthy participants.
Interventions
- DRUG Midazolam
- DRUG Mitapivat
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-10-17 |
| Est. Completion | 2024-12-03 |
| Phase | Phase 1 |
What the finished NCT06648824 record still lists
NCT06648824 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 2 interventions - of which Midazolam is the first listed.
NCT06648824 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06648824 about?
NCT06648824 is a clinical study titled "Study of How Mitapivat Affects Midazolam Blood Levels in Healthy Participants". The primary purpose of this study is to assess the effect of mitapivat on the single oral dose pharmacokinetics (PK) of midazolam in healthy participants.
What is the current status of trial NCT06648824?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2024-10-17. Estimated completion is 2024-12-03.
What interventions are being tested in trial NCT06648824?
The interventions under investigation include: Midazolam (DRUG), Mitapivat (DRUG).
Who is sponsoring clinical trial NCT06648824?
This trial is sponsored by Agios Pharmaceuticals, which has 44 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06648824's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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