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NCT06648668 · ClinicalTrials.gov registry record · Phase 1
A Study to Investigate the Interaction Between TMP-301 and Cocaine.
A Phase 1 study, sponsored by Tempero Bio.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
NCT06648668: Completed Phase 1 study, sponsored by Tempero Bio.
NCT06648668 is a Phase 1 study that has completed, run by Tempero Bio. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06648668, a Phase 1 study, has completed, sponsored by Tempero Bio.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
Study Summary
This will be a randomized, double-blind, placebo-controlled, parallel-group study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of oral TMP-301, given concurrently with cocaine. The study will consist of 4 phases: Screening, Baseline, Treatment, and Follow-up.
Interventions
- DRUG Placebo
- DRUG TMP-301
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2025-01-04 |
| Est. Completion | 2025-05-05 |
| Phase | Phase 1 |
What the finished NCT06648668 record still lists
NCT06648668 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT06648668 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06648668 about?
NCT06648668 is a clinical study titled "A Study to Investigate the Interaction Between TMP-301 and Cocaine.". This will be a randomized, double-blind, placebo-controlled, parallel-group study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of oral TMP-301, given concurrently with cocaine. The study will consist of 4 phases: Screening, Baseline, Treatment, and Follow-up.
What is the current status of trial NCT06648668?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2025-01-04. Estimated completion is 2025-05-05.
What interventions are being tested in trial NCT06648668?
The interventions under investigation include: Placebo (DRUG), TMP-301 (DRUG).
Who is sponsoring clinical trial NCT06648668?
This trial is sponsored by Tempero Bio, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06648668's enrollment target sits among peer trials
18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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