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NCT06639854 · ClinicalTrials.gov registry record · NA
The Use of Cytomegalovirus Cell Mediated Immunity to Optimize the Duration of Letermovir Prophylaxis in Hematopoietic Cell Transplant Recipients
A NA study of Hematopoietic Cell Transplant and Cytomegalovirus Cell Mediated Immunity, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 105
- Enrollment target
- 1
- Study location
NCT06639854: Recruiting NA study of Hematopoietic Cell Transplant and Cytomegalovirus Cell Mediated Immunity, sponsored by M.D. Anderson Cancer Center.
NCT06639854 is a NA study of Hematopoietic Cell Transplant and Cytomegalovirus Cell Mediated Immunity that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 105 participants, below the 372-participant average among 6 other Hematopoietic Cell Transplant trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06639854, a NA study of Hematopoietic Cell Transplant and Cytomegalovirus Cell Mediated Immunity, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 105 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this laboratory research study is to learn if interrupting a patient's letermovir dosing based on their immune system response can help HSC transplant patients avoid post-treatment CMV infections better than taking letermovir every day without interruption.
Primary Outcome
Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0
Conditions Studied
Interventions
- DRUG Letermovir
- PROCEDURE Hematopoietic Cell Transplant
Study Locations (1)
Texas
- The University of Texas MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2024-11-20 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT06639854 shows while recruiting
NCT06639854 is an interventional study that assigns participants to a tested intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, below the 372-participant average among 6 other Hematopoietic Cell Transplant trials with a reported enrollment target (72% lower).
The record links to 2 conditions, with Hematopoietic Cell Transplant appearing as the primary indexed condition, and to 2 interventions - of which Letermovir is the first listed.
NCT06639854 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06639854 about?
NCT06639854 is a clinical study titled "The Use of Cytomegalovirus Cell Mediated Immunity to Optimize the Duration of Letermovir Prophylaxis in Hematopoietic Cell Transplant Recipients". The goal of this laboratory research study is to learn if interrupting a patient's letermovir dosing based on their immune system response can help HSC transplant patients avoid post-treatment CMV infections better than taking letermovir every day without interruption.
What is the current status of trial NCT06639854?
This trial is currently recruiting. It is a NA study. The enrollment target is 105 participants. The study started on 2024-11-20. Estimated completion is 2026-12-31.
What conditions does trial NCT06639854 study?
This clinical trial studies the following conditions: Hematopoietic Cell Transplant, Cytomegalovirus Cell Mediated Immunity.
What interventions are being tested in trial NCT06639854?
The interventions under investigation include: Letermovir (DRUG), Hematopoietic Cell Transplant (PROCEDURE).
Who is sponsoring clinical trial NCT06639854?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06639854 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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