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NCT06627244 · ClinicalTrials.gov registry record · Phase 2

Study of Tebentafusp and Radioembolization in the Treatment of Metastatic Uveal Melanoma

A Phase 2 study of Metastatic Uveal Melanoma and Metastatic Uveal Melanoma in the Liver, sponsored by University of Miami.

Recruiting
Registry status
Phase 2
Development phase
30
Enrollment target
1
Study location

NCT06627244 is a Phase 2 study of Metastatic Uveal Melanoma and Metastatic Uveal Melanoma in the Liver that is actively recruiting participants, run by University of Miami. The registered enrollment target is 30 participants, below the 130-participant average among 14 other Metastatic Uveal Melanoma trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06627244, a Phase 2 study of Metastatic Uveal Melanoma and Metastatic Uveal Melanoma in the Liver, is actively recruiting participants, sponsored by University of Miami.

RECRUITING
Registry status
Phase 2
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine the effects (good and bad) that Tebentafusp in combination with Yttrium-90 (Y-90) radioembolization has on patients with metastatic uveal melanoma that has spread to the liver.

Interventions

  • RADIATION TheraSphere™ Yttrium-90 Trans-Arterial Radioembolization
  • DRUG Tebentafusp

Study Locations (1)

Florida

  • University of Miami - Miami

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-02-14
Est. Completion 2031-02-17
Phase Phase 2

Sponsor

University of Miami

721 total trials

What the Registry Record Tells You About NCT06627244

The ClinicalTrials.gov registry entry for NCT06627244 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 130-participant average among 14 other Metastatic Uveal Melanoma trials with a reported enrollment target (77% lower). The listed sponsor is University of Miami, which has 721 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Metastatic Uveal Melanoma appearing as the primary indexed condition, and to 2 interventions - of which TheraSphere™ Yttrium-90 Trans-Arterial Radioembolization is the first listed.

NCT06627244 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT06627244 about?

NCT06627244 is a clinical study titled "Study of Tebentafusp and Radioembolization in the Treatment of Metastatic Uveal Melanoma". The purpose of this study is to determine the effects (good and bad) that Tebentafusp in combination with Yttrium-90 (Y-90) radioembolization has on patients with metastatic uveal melanoma that has spread to the liver.

What is the current status of trial NCT06627244?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2025-02-14. Estimated completion is 2031-02-17.

What conditions does trial NCT06627244 study?

This clinical trial studies the following conditions: Metastatic Uveal Melanoma, Metastatic Uveal Melanoma in the Liver.

What interventions are being tested in trial NCT06627244?

The interventions under investigation include: TheraSphere™ Yttrium-90 Trans-Arterial Radioembolization (RADIATION), Tebentafusp (DRUG).

Who is sponsoring clinical trial NCT06627244?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06627244 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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