Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06625502 · ClinicalTrials.gov registry record · NA
Unmute's CARE Framework: A Novel Approach to Strengthen the Therapeutic Alliance and Reduce Treatment Disparities
A NA study of Anxiety Symptoms and Depression Scale Score, sponsored by New York University.
- Active
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 2
- Study locations
NCT06625502: Active NA study of Anxiety Symptoms and Depression Scale Score, sponsored by New York University.
NCT06625502 is a NA study of Anxiety Symptoms and Depression Scale Score that is active but no longer recruiting, run by New York University. The registered enrollment target is 40 participants, below the 178-participant average among 5 other Anxiety Symptoms trials with a reported enrollment target (78% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06625502, a NA study of Anxiety Symptoms and Depression Scale Score, is active but no longer recruiting, sponsored by New York University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 2
- Study locations
Study Summary
Aim 1: Expand and adapt the CARE framework to train providers to cultivate a strong early alliance with patients who do not share their background (e.g., mismatched dyads). Aim 2: Establish the feasibility, acceptability, and preliminary effectiveness of the adapted CARE framework in mismatched dyads involving 8 providers and 40 patients receiving 15 sessions of teletherapy. The goal of this clinical trial is to learn if a new CARE intervention works to improve the cultural fit of psychotherapy for diverse populations, even when the therapist and patient do not share the same cultural background. We will refine and test the intervention with a sample of therapists working with Asian American participants receiving short-term individual psychotherapy delivered online. The main questions the study aims to answer are: * Does the CARE framework, adapted for and delivered by therapists specifically trained to work with patients who do not share their background (e.g., mismatched dyads), improve treatment engagement and retention? * Is the CARE framework associated with a) the development of a positive therapeutic relationship between mismatched patient-therapist dyads and b) significant improvements in participants' presenting problems? Participants will: * Receive up to 15 weekly sessions of individual psychotherapy * Complete different online surveys after every session and on a monthly basis
Primary Outcome
A brief scale for measuring treatment expectancy and rationale credibility for use in clinical outcome studies. Given that Asian American have the lowest rates of mental health service utilization and high dropout rates, we will set conservative success criteria for acceptability, defined as (a) a mean score \> 5 (on a 1-9 scale) for the 3 credibility items of the Credibility/Expectancy Questionnaire.
Conditions Studied
Interventions
- BEHAVIORAL Culturally-Affirming Racial Equity Framework
Study Locations (2)
Massachusetts
- Unmute Enterprise Inc. [A telehealth company] - Chelsea
New York
- Virtual/Telehealth - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-09-15 |
| Est. Completion | 2026-06-01 |
| Phase | NA |
What the registry record for NCT06625502 still lists
NCT06625502 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 178-participant average among 5 other Anxiety Symptoms trials with a reported enrollment target (78% lower).
The record links to 4 conditions, with Anxiety Symptoms appearing as the primary indexed condition, and to 1 intervention - of which Culturally-Affirming Racial Equity Framework is the first listed.
NCT06625502 reports a single indexed study location in Massachusetts, New York.
Frequently Asked Questions
What is clinical trial NCT06625502 about?
NCT06625502 is a clinical study titled "Unmute's CARE Framework: A Novel Approach to Strengthen the Therapeutic Alliance and Reduce Treatment Disparities". Aim 1: Expand and adapt the CARE framework to train providers to cultivate a strong early alliance with patients who do not share their background (e.g., mismatched dyads). Aim 2: Establish the feasibility, acceptability, and preliminary effectiveness of the adapted CARE framework in mismatched dyad...
What is the current status of trial NCT06625502?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-09-15. Estimated completion is 2026-06-01.
What conditions does trial NCT06625502 study?
This clinical trial studies the following conditions: Anxiety Symptoms, Depression Scale Score, Functioning, Psychosocial, Working Alliance.
What interventions are being tested in trial NCT06625502?
The interventions under investigation include: Culturally-Affirming Racial Equity Framework (BEHAVIORAL).
Who is sponsoring clinical trial NCT06625502?
This trial is sponsored by New York University, which has 83 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06625502 being conducted?
This trial has 2 study locations across Massachusetts, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Anxiety Symptoms
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Video-feedback Intervention to Promote Racial-Ethnic Socialization Competency (VIP-RACE)
RECRUITING · NA
-
Strengthening Health and Insight in New Educators
RECRUITING · NA
-
Mirror Journaling App Study
ACTIVE NOT RECRUITING · NA
-
Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology
COMPLETED · NA
-
Attachment and Biobehavioral Catch-up for Depression
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01306019 · 40 participants · Phase 1
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
- NCT01608152 · 40 participants
Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors
- NCT01668082 · 40 participants · NA
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
- NCT02015013 · 40 participants · Phase 2
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI