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NCT06607406 · ClinicalTrials.gov registry record · NA
Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery
A NA study of Head and Neck Cancer and Head and Neck Squamous Cell Carcinoma (HNSCC), sponsored by Wake Forest University Health Sciences.
- Recruiting
- Registry status
- NA
- Development phase
- 75
- Enrollment target
- 3
- Study locations
NCT06607406: Recruiting NA study of Head and Neck Cancer and Head and Neck Squamous Cell Carcinoma (HNSCC), sponsored by Wake Forest University Health Sciences.
NCT06607406 is a NA study of Head and Neck Cancer and Head and Neck Squamous Cell Carcinoma (HNSCC) that is actively recruiting participants, run by Wake Forest University Health Sciences. The registered enrollment target is 75 participants, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (71% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06607406, a NA study of Head and Neck Cancer and Head and Neck Squamous Cell Carcinoma (HNSCC), is actively recruiting participants, sponsored by Wake Forest University Health Sciences.
- RECRUITING
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
- 3
- Study locations
Study Summary
The goal of this clinical trial is to determine whether accelerated radiotherapy (involving 6 treatments per week) is better than standard radiotherapy (involving 5 treatments per week) at treating cancer of the head and neck when initiated more than 6 weeks after surgery.
Primary Outcome
Time to locoregional recurrence, will be assessed on an intention to treat basis using a one-sided log rank test to compare hazard rates between groups. Kaplan-Meier survival curves will also be generated with locoregional failure or death as the event of interest and last clinical disease assessment as a right-censor.
Conditions Studied
Interventions
- RADIATION Accelerated radiotherapy
- RADIATION Conventional radiotherapy
Study Locations (3)
North Carolina
- Levine Cancer Institute - Charlotte
- Wake Forest Baptist Comprehensive Cancer Center - Winston-Salem
Wisconsin
- Advocate Aurora Radiation Oncology - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2025-01-21 |
| Est. Completion | 2030-01 |
| Phase | NA |
What NCT06607406 shows while recruiting
NCT06607406 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (71% lower).
The record links to 2 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 2 interventions - of which Accelerated radiotherapy is the first listed.
NCT06607406 reports a single indexed study location in North Carolina, Wisconsin.
Frequently Asked Questions
What is clinical trial NCT06607406 about?
NCT06607406 is a clinical study titled "Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery". The goal of this clinical trial is to determine whether accelerated radiotherapy (involving 6 treatments per week) is better than standard radiotherapy (involving 5 treatments per week) at treating cancer of the head and neck when initiated more than 6 weeks after surgery.
What is the current status of trial NCT06607406?
This trial is currently recruiting. It is a NA study. The enrollment target is 75 participants. The study started on 2025-01-21. Estimated completion is 2030-01.
What conditions does trial NCT06607406 study?
This clinical trial studies the following conditions: Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma (HNSCC).
What interventions are being tested in trial NCT06607406?
The interventions under investigation include: Accelerated radiotherapy (RADIATION), Conventional radiotherapy (RADIATION).
Who is sponsoring clinical trial NCT06607406?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06607406 being conducted?
This trial has 3 study locations across North Carolina, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Head and Neck Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06607406's enrollment target sits among peer trials
75 100th of 250 higher than 149 of 250 other Head and Neck Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Head and Neck Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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