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NCT06576856 · ClinicalTrials.gov registry record

Salivary Markers in Periodontal Disorders

A clinical trial of Periodontal Disease, Staging, Salivary Markers, Diagnosis, sponsored by Midwestern University.

Completed
Registry status
106
Enrollment target
1
Study location

NCT06576856 is a study of Periodontal Disease, Staging, Salivary Markers, Diagnosis that has completed, run by Midwestern University. The registered enrollment target is 106 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT06576856, a study of Periodontal Disease, Staging, Salivary Markers, Diagnosis, has completed, sponsored by Midwestern University.

COMPLETED
Registry status
106 participants
Enrollment target
1
Study location

Study Summary

The swelling of the gum, or periodontitis, is the leading cause for tooth loss, and currently affects up to 65 million adults only in the United States. One of the reasons for the widespread of periodontitis is because currently there are no definitive methods to detect the onset of gum disease. This lack of foresight impedes medical professionals to enact any preventive measures before the disease already manifests itself. We wish to expand our understanding towards the development of periodontitis by studying the expression and activity of salivary markers that have been associated with advanced stages of the disease, wherein the supporting tissues of tooth (periodontium) are already irreversibly destroyed. We hypothesize that a progressive shift in the expression of such salivary markers can indicate a change or evolution of periodontitis staging. In specific, we seek to establish a quantifiable relationship among levels of salivary proteases called MMPs, level of metal ions in different stages varying from health to periodontitis. The overall goal of this proposal is to enhance the predictability of periodontitis, as we are currently unable to diagnose the disease until the manifestation of its clinical signs and symptoms.

Interventions

  • OTHER This is an observational study, no intervention is anticipated.

Study Locations (1)

Illinois

  • Midwestern Univerity - Downers Grove

Trial Details

FieldValue
Enrollment Target 106 participants
Start Date 2021-11-06
Est. Completion 2024-10-10

Sponsor

Midwestern University

15 total trials

What the Registry Record Tells You About NCT06576856

The ClinicalTrials.gov registry entry for NCT06576856 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 106 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Midwestern University, which has 15 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Periodontal Disease, Staging, Salivary Markers, Diagnosis appearing as the primary indexed condition, and to 1 intervention - of which This is an observational study, no intervention is anticipated. is the first listed.

NCT06576856 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT06576856 about?

NCT06576856 is a clinical study titled "Salivary Markers in Periodontal Disorders". The swelling of the gum, or periodontitis, is the leading cause for tooth loss, and currently affects up to 65 million adults only in the United States. One of the reasons for the widespread of periodontitis is because currently there are no definitive methods to detect the onset of gum disease. Thi...

What is the current status of trial NCT06576856?

This trial is currently completed. The enrollment target is 106 participants. The study started on 2021-11-06. Estimated completion is 2024-10-10.

What conditions does trial NCT06576856 study?

This clinical trial studies the following conditions: Periodontal Disease, Staging, Salivary Markers, Diagnosis.

What interventions are being tested in trial NCT06576856?

The interventions under investigation include: This is an observational study, no intervention is anticipated. (OTHER).

Who is sponsoring clinical trial NCT06576856?

This trial is sponsored by Midwestern University, which has 15 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06576856 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.