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NCT06576856 · ClinicalTrials.gov registry record
Salivary Markers in Periodontal Disorders
A clinical trial of Periodontal Disease, Staging, Salivary Markers, Diagnosis, sponsored by Midwestern University.
- Completed
- Registry status
- 106
- Enrollment target
- 1
- Study location
NCT06576856: Completed study of Periodontal Disease, Staging, Salivary Markers, Diagnosis, sponsored by Midwestern University.
NCT06576856 is a study of Periodontal Disease, Staging, Salivary Markers, Diagnosis that has completed, run by Midwestern University. The registered enrollment target is 106 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06576856, a study of Periodontal Disease, Staging, Salivary Markers, Diagnosis, has completed, sponsored by Midwestern University.
- COMPLETED
- Registry status
- 106 participants
- Enrollment target
- 1
- Study location
Study Summary
The swelling of the gum, or periodontitis, is the leading cause for tooth loss, and currently affects up to 65 million adults only in the United States. One of the reasons for the widespread of periodontitis is because currently there are no definitive methods to detect the onset of gum disease. This lack of foresight impedes medical professionals to enact any preventive measures before the disease already manifests itself. We wish to expand our understanding towards the development of periodontitis by studying the expression and activity of salivary markers that have been associated with advanced stages of the disease, wherein the supporting tissues of tooth (periodontium) are already irreversibly destroyed. We hypothesize that a progressive shift in the expression of such salivary markers can indicate a change or evolution of periodontitis staging. In specific, we seek to establish a quantifiable relationship among levels of salivary proteases called MMPs, level of metal ions in different stages varying from health to periodontitis. The overall goal of this proposal is to enhance the predictability of periodontitis, as we are currently unable to diagnose the disease until the manifestation of its clinical signs and symptoms.
Primary Outcome
Levels of MMPs assessed by different immuno-assays.
Conditions Studied
Interventions
- OTHER This is an observational study, no intervention is anticipated.
Study Locations (1)
Illinois
- Midwestern Univerity - Downers Grove
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 106 participants |
| Start Date | 2021-11-06 |
| Est. Completion | 2024-10-10 |
What the finished NCT06576856 record still lists
NCT06576856 is an observational study that tracks outcomes without assigning an intervention. The registered 106 participants enrollment target is mid-sized for trials with a published cap.
The record links to 1 condition, with Periodontal Disease, Staging, Salivary Markers, Diagnosis appearing as the primary indexed condition, and to 1 intervention - of which This is an observational study, no intervention is anticipated. is the first listed.
NCT06576856 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT06576856 about?
NCT06576856 is a clinical study titled "Salivary Markers in Periodontal Disorders". The swelling of the gum, or periodontitis, is the leading cause for tooth loss, and currently affects up to 65 million adults only in the United States. One of the reasons for the widespread of periodontitis is because currently there are no definitive methods to detect the onset of gum disease. Thi...
What is the current status of trial NCT06576856?
This trial is currently completed. The enrollment target is 106 participants. The study started on 2021-11-06. Estimated completion is 2024-10-10.
What conditions does trial NCT06576856 study?
This clinical trial studies the following conditions: Periodontal Disease, Staging, Salivary Markers, Diagnosis.
What interventions are being tested in trial NCT06576856?
The interventions under investigation include: This is an observational study, no intervention is anticipated. (OTHER).
Who is sponsoring clinical trial NCT06576856?
This trial is sponsored by Midwestern University, which has 15 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06576856 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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