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NCT06561087 · ClinicalTrials.gov registry record · Phase 2

Phase II Randomized, Placebo- Controlled Study of Intralesional Nivolumab for High-risk Oral Premalignant Lesions

A Phase 2 study of Premalignant Lesion, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
45
Enrollment target
1
Study location

NCT06561087 is a Phase 2 study of Premalignant Lesion that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 45 participants, below the 232-participant average among 4 other Premalignant Lesion trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06561087, a Phase 2 study of Premalignant Lesion, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
45 participants
Enrollment target
1
Study location

Study Summary

To evaluate the antitumor efficacy of intralesional injections of nivolumab in patients with high-risk oral premalignant lesions

Conditions Studied

Interventions

  • DRUG Nivolumab

Study Locations (1)

Texas

  • MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2025-02-27
Est. Completion 2029-05-30
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT06561087

The ClinicalTrials.gov registry entry for NCT06561087 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 232-participant average among 4 other Premalignant Lesion trials with a reported enrollment target (81% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Premalignant Lesion appearing as the primary indexed condition, and to 1 intervention - of which Nivolumab is the first listed.

NCT06561087 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT06561087 about?

NCT06561087 is a clinical study titled "Phase II Randomized, Placebo- Controlled Study of Intralesional Nivolumab for High-risk Oral Premalignant Lesions". To evaluate the antitumor efficacy of intralesional injections of nivolumab in patients with high-risk oral premalignant lesions

What is the current status of trial NCT06561087?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 45 participants. The study started on 2025-02-27. Estimated completion is 2029-05-30.

What conditions does trial NCT06561087 study?

This clinical trial studies the following conditions: Premalignant Lesion.

What interventions are being tested in trial NCT06561087?

The interventions under investigation include: Nivolumab (DRUG).

Who is sponsoring clinical trial NCT06561087?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06561087 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.