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NCT06556368 · ClinicalTrials.gov registry record · Phase 3
A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK
A Phase 3 study of Wet Age-related Macular Degeneration, sponsored by Kodiak Sciences.
- Active
- Registry status
- Phase 3
- Development phase
- 675
- Enrollment target
- 20
- Study locations
NCT06556368 is a Phase 3 study of Wet Age-related Macular Degeneration that is active but no longer recruiting, run by Kodiak Sciences. The registered enrollment target is 675 participants, above the 340-participant average among 8 other Wet Age-related Macular Degeneration trials with a reported enrollment target (99% higher). The trial reports 20 study locations across 7 states.
The verdict
NCT06556368, a Phase 3 study of Wet Age-related Macular Degeneration, is active but no longer recruiting, sponsored by Kodiak Sciences.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 675 participants
- Enrollment target
- 20
- Study locations
Study Summary
A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants with Neovascular (Wet) Age-related Macular Degeneration (wAMD)
Conditions Studied
Interventions
- DRUG Aflibercept
- DRUG Tarcocimab tedromer
- DRUG Tabirafusp tedromer
Study Locations (20)
California
- Retina Consultants of Orange County - Fullerton
- Global Research Management, Inc. - Lugene Eye Institute - Glendale
- Retinal Consultants Medical Group, Inc. - Modesto
- California Eye Specialists Medical Group, Inc. - Pasadena
- California Eye Specialists Medical Group, Inc. - Redlands
- Retinal Consultants Medical Group Inc - Sacramento
Florida
- Blue Ocean Clinical Research - Clearwater
- Retina Group of Florida - Fort Lauderdale
- National Ophthalmic Research Institute - Fort Myers
- Retina Group of Florida - Sarasota
- Center for Retina and Macular Disease - Winter Haven
Arizona
- Associated Retina Consultants - Gilbert
- Associated Retina Consultants - Phoenix
- Retina Macula Institute of Arizona - Scottsdale
- Retina Associates SW - Tucson
Illinois
- Retina Associates, Ltd - Elmhurst
- Illinois Retina Associates - Oak Park
Colorado
- Retina Consultants of Southern Colorado - Colorado Springs
Connecticut
- Retina Group of New England, PC - Waterford
Georgia
- Southeast Retina Center - Augusta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 675 participants |
| Start Date | 2024-08-23 |
| Est. Completion | 2027-08 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06556368
The ClinicalTrials.gov registry entry for NCT06556368 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 675 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 340-participant average among 8 other Wet Age-related Macular Degeneration trials with a reported enrollment target (99% higher). The listed sponsor is Kodiak Sciences, which has 11 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Wet Age-related Macular Degeneration appearing as the primary indexed condition, and to 3 interventions - of which Aflibercept is the first listed.
NCT06556368 reports 20 study locations spanning 7 distinct geographic areas - top geographies include California, Florida, Arizona.
Frequently Asked Questions
What is clinical trial NCT06556368 about?
NCT06556368 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK". A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants with Neovascular (Wet) Age-related Macular Degeneration (wAMD)
What is the current status of trial NCT06556368?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 675 participants. The study started on 2024-08-23. Estimated completion is 2027-08.
What conditions does trial NCT06556368 study?
This clinical trial studies the following conditions: Wet Age-related Macular Degeneration.
What interventions are being tested in trial NCT06556368?
The interventions under investigation include: Aflibercept (DRUG), Tarcocimab tedromer (DRUG), Tabirafusp tedromer (DRUG).
Who is sponsoring clinical trial NCT06556368?
This trial is sponsored by Kodiak Sciences, which has 11 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06556368 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.