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NCT06545682 · ClinicalTrials.gov registry record · Phase 1

Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)

A Phase 1 study of Breast Cancer and Melanoma (Skin Cancer), sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 1
Development phase
50
Enrollment target
1
Study location

NCT06545682 is a Phase 1 study of Breast Cancer and Melanoma (Skin Cancer) that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 50 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06545682, a Phase 1 study of Breast Cancer and Melanoma (Skin Cancer), is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 1
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

To find a recommended dose of the combination of alpelisib and pembrolizumab that can be given to patients with metastatic breast cancer or melanoma.

Interventions

  • DRUG Alpelisib + Pembrolizumab

Study Locations (1)

Texas

  • MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2024-10-15
Est. Completion 2029-08-03
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT06545682

The ClinicalTrials.gov registry entry for NCT06545682 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which Alpelisib + Pembrolizumab is the first listed.

NCT06545682 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT06545682 about?

NCT06545682 is a clinical study titled "Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)". To find a recommended dose of the combination of alpelisib and pembrolizumab that can be given to patients with metastatic breast cancer or melanoma.

What is the current status of trial NCT06545682?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2024-10-15. Estimated completion is 2029-08-03.

What conditions does trial NCT06545682 study?

This clinical trial studies the following conditions: Breast Cancer, Melanoma (Skin Cancer), Brain Metastasases.

What interventions are being tested in trial NCT06545682?

The interventions under investigation include: Alpelisib + Pembrolizumab (DRUG).

Who is sponsoring clinical trial NCT06545682?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06545682 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.