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NCT06543316 · ClinicalTrials.gov registry record · NA
Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment
A NA study of Abdominal Pain and Nausea, sponsored by Christopher C. Thompson, MD, MSc.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06543316: Recruiting NA study of Abdominal Pain and Nausea, sponsored by Christopher C. Thompson, MD, MSc.
NCT06543316 is a NA study of Abdominal Pain and Nausea that is actively recruiting participants, run by Christopher C. Thompson, MD, MSc. The registered enrollment target is 100 participants, below the 145-participant average among 19 other Abdominal Pain trials with a reported enrollment target (31% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06543316, a NA study of Abdominal Pain and Nausea, is actively recruiting participants, sponsored by Christopher C. Thompson, MD, MSc.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of the study is to investigate the treatment of marginal ulcers with Low Thermal plasma in an endoscopic setting. By a treatment of the ulcerated areas with argon plasma with low power settings (\~ 1 W) we hypothesize that the size of the ulcers will shrink, and the healing is accelerated compared to standard of care alone. Patients will benefit from this minimally invasive approach compared to a much more invasive surgical approach that comes with higher risks and hospital stay length time. From a societal and scientific perspective, this study aims to extend the well-documented clinical benefits of plasma technology - from external wound healing to internal ulcer treatment - within an endoscopic framework. The success of this study could pave the way for broader applications of LTP in the treatment of other endoscopically accessible conditions such as peptic ulcers, duodenal ulcers and esophageal ulcers. This advancement has the potential not only to improve patient outcomes through less invasive methods, but also to position LTP as a cornerstone in the future of gastroenterological wound management strategies.
Primary Outcome
Complete healing or significant reduction in ulcer size, determined by endoscopic evaluation at the first follow-up (4 weeks +/- 1 week) and at the end of the second follow-up period (8 weeks +/- 2 weeks).
Conditions Studied
Interventions
- PROCEDURE Low Thermal Plasma (LTP) Treatment
- OTHER Standard of Care Ulcer Treatment (typically PPI Administration)
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-03-04 |
| Est. Completion | 2027-04-30 |
| Phase | NA |
What NCT06543316 shows while recruiting
NCT06543316 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 145-participant average among 19 other Abdominal Pain trials with a reported enrollment target (31% lower).
The record links to 10 conditions, with Abdominal Pain appearing as the primary indexed condition, and to 2 interventions - of which Low Thermal Plasma (LTP) Treatment is the first listed.
NCT06543316 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06543316 about?
NCT06543316 is a clinical study titled "Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment". The objective of the study is to investigate the treatment of marginal ulcers with Low Thermal plasma in an endoscopic setting. By a treatment of the ulcerated areas with argon plasma with low power settings (\~ 1 W) we hypothesize that the size of the ulcers will shrink, and the healing is accelera...
What is the current status of trial NCT06543316?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2025-03-04. Estimated completion is 2027-04-30.
What conditions does trial NCT06543316 study?
This clinical trial studies the following conditions: Abdominal Pain, Nausea, Ulcer, Vomiting, GastroIntestinal Bleeding.
What interventions are being tested in trial NCT06543316?
The interventions under investigation include: Low Thermal Plasma (LTP) Treatment (PROCEDURE), Standard of Care Ulcer Treatment (typically PPI Administration) (OTHER).
Who is sponsoring clinical trial NCT06543316?
This trial is sponsored by Christopher C. Thompson, MD, MSc, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06543316 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06543316's enrollment target sits among peer trials
100 13th of 19 higher than 7 of 19 other Abdominal Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Abdominal Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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