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NCT06535178 · ClinicalTrials.gov registry record · NA
The Influence of Sleep on Cardiovascular Outcomes
A NA study of Pain and Circadian Rhythm, sponsored by Oregon Health and Science University.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT06535178: Recruiting NA study of Pain and Circadian Rhythm, sponsored by Oregon Health and Science University.
NCT06535178 is a NA study of Pain and Circadian Rhythm that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 30 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06535178, a NA study of Pain and Circadian Rhythm, is actively recruiting participants, sponsored by Oregon Health and Science University.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to identify the effects of sleep regularity on cardiovascular regulatory mechanisms. The investigators are hoping to discover if improving the regularity of sleep timing will improve metabolic and vascular health markers. The protocol is a 12-week prospective cohort study that includes both field and in-laboratory data collection in ostensibly healthy male and female adults, aged 18-40years. We will also have a sub-group of individuals with chronic pain to examine the effects of sleep regularity on pain outcomes.
Primary Outcome
Saliva samples will be collected pre- and post-12-week intervention and will be assayed for melatonin using standardized assays. Dim-light melatonin onset will be calculated using the linear interpolated point in time in which each participant's melatonin crosses and remains elevated above a 4pg/mL threshold. Examined using planned comparison dependent t-tests to compare the changes pre- and post-12-weeks.
Conditions Studied
Interventions
- BEHAVIORAL Sleep Regularity Group
Study Locations (1)
Oregon
- Oregon Health & Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2024-07-01 |
| Est. Completion | 2026-09-30 |
| Phase | NA |
What NCT06535178 shows while recruiting
NCT06535178 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (90% lower).
The record links to 4 conditions, with Pain appearing as the primary indexed condition, and to 1 intervention - of which Sleep Regularity Group is the first listed.
NCT06535178 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT06535178 about?
NCT06535178 is a clinical study titled "The Influence of Sleep on Cardiovascular Outcomes". The goal of this study is to identify the effects of sleep regularity on cardiovascular regulatory mechanisms. The investigators are hoping to discover if improving the regularity of sleep timing will improve metabolic and vascular health markers. The protocol is a 12-week prospective cohort study t...
What is the current status of trial NCT06535178?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2024-07-01. Estimated completion is 2026-09-30.
What conditions does trial NCT06535178 study?
This clinical trial studies the following conditions: Pain, Circadian Rhythm, Cardiometabolic Health, Vascular Health.
What interventions are being tested in trial NCT06535178?
The interventions under investigation include: Sleep Regularity Group (BEHAVIORAL).
Who is sponsoring clinical trial NCT06535178?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06535178 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06535178's enrollment target sits among peer trials
30 310th of 374 higher than 60 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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