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NCT06529523 · ClinicalTrials.gov registry record · Phase 2
Tislelizumab in People With Colorectal Cancer
A Phase 2 study of Colorectal Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 3
- Study locations
NCT06529523: Recruiting Phase 2 study of Colorectal Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
NCT06529523 is a Phase 2 study of Colorectal Cancer that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 40 participants, below the 1,545-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (97% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06529523, a Phase 2 study of Colorectal Cancer, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 3
- Study locations
Study Summary
The researchers are doing this study to find out whether tislelizumab is an effective treatment for people with colorectal cancer who are living in Nigeria. The researchers will also look at the safety of the study drug. All participants in this study will be treatment naïve (they have not yet received treatment for their cancer), and their cancer will be mismatch repair deficient (dMMR). dMMR cancer can happen when your cells are unable to repair mistakes made during the cell division process.
Primary Outcome
(ORR, defined as CR or PR) as measured by RECIST 1.1 in patients with mismatch repair deficient metastatic colorectal adenocarcinoma (cohort 1) and in patients with mismatch repair deficient localized (stage II/III) rectal adenocarcinoma (cohort 2).
Conditions Studied
Interventions
- DRUG Tislelizumab
Study Locations (3)
New York
- Memorial Sloan Kettering Cancer Center - New York
Lagos
- Lagos University Teaching Hospital - Idi Araba
Other
- Obafemi Awolowo University Teaching Hospital - Ile-Ife
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2024-07-26 |
| Est. Completion | 2028-07 |
| Phase | Phase 2 |
What NCT06529523 shows while recruiting
NCT06529523 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,545-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention - of which Tislelizumab is the first listed.
NCT06529523 reports a single indexed study location in New York, Lagos, Other.
Frequently Asked Questions
What is clinical trial NCT06529523 about?
NCT06529523 is a clinical study titled "Tislelizumab in People With Colorectal Cancer". The researchers are doing this study to find out whether tislelizumab is an effective treatment for people with colorectal cancer who are living in Nigeria. The researchers will also look at the safety of the study drug. All participants in this study will be treatment naïve (they have not yet rece...
What is the current status of trial NCT06529523?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2024-07-26. Estimated completion is 2028-07.
What conditions does trial NCT06529523 study?
This clinical trial studies the following conditions: Colorectal Cancer.
What interventions are being tested in trial NCT06529523?
The interventions under investigation include: Tislelizumab (DRUG).
Who is sponsoring clinical trial NCT06529523?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06529523 being conducted?
This trial has 3 study locations across New York, Lagos. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colorectal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06529523's enrollment target sits among peer trials
40 298th of 381 higher than 76 of 381 other Colorectal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colorectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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