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NCT06518356 · ClinicalTrials.gov registry record · NA
Mastoid taVNS-fMRI
A NA study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT06518356: Completed NA study, sponsored by Medical University of South Carolina.
NCT06518356 is a NA study that has completed, run by Medical University of South Carolina. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06518356, a NA study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
The purpose of this study is to explore whether stimulating different outer parts of the ear using a non-invasive form of ear stimulation called transcutaneous auricular vagus nerve stimulation (taVNS) will create different brain activation images. Investigators will recruit 24 healthy participants. The ear stimulation will be delivered while taking brain images using a magnetic resonance imaging (MRI) machine.
Primary Outcome
taVNS will be administered to participants within the bore of the MRI scanner while the investigators acquire high-resolution functional neuroimaging. Both a general linear model and SNM approach will be used to examine BOLD signal changes during stimulation relative to rest blocks, comparing each of the 3 stimulation targets within- and between- subjects to identify any differences in brain activity during stimulation of the mastoid site compared to the cymba site and sham site.
Interventions
- DEVICE Transcutaneous Auricular Neurostimulation (tAN)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2024-08-26 |
| Est. Completion | 2025-04-28 |
| Phase | NA |
What the finished NCT06518356 record still lists
NCT06518356 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Transcutaneous Auricular Neurostimulation (tAN) is the first listed.
NCT06518356 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06518356 about?
NCT06518356 is a clinical study titled "Mastoid taVNS-fMRI". The purpose of this study is to explore whether stimulating different outer parts of the ear using a non-invasive form of ear stimulation called transcutaneous auricular vagus nerve stimulation (taVNS) will create different brain activation images. Investigators will recruit 24 healthy participants....
What is the current status of trial NCT06518356?
This trial is currently completed. It is a NA study. The enrollment target is 24 participants. The study started on 2024-08-26. Estimated completion is 2025-04-28.
What interventions are being tested in trial NCT06518356?
The interventions under investigation include: Transcutaneous Auricular Neurostimulation (tAN) (DEVICE).
Who is sponsoring clinical trial NCT06518356?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06518356's enrollment target sits among peer trials
24 1736th of 2000 higher than 246 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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