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NCT06507735 · ClinicalTrials.gov registry record · NA
The Effects of Mannose Supplementation on Glycosylation and Protein Levels in Human Sera
A NA study, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 6
- Enrollment target
NCT06507735: Completed NA study, sponsored by University of Texas Southwestern Medical Center.
NCT06507735 is a NA study that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 6 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06507735, a NA study, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 6 participants
- Enrollment target
Study Summary
The purpose of our study is to investigate the effects of supplemental mannose on sera of humans who are healthy. We will perform proteomics studies to elucidate changes to glycan structure and protein level changes. We hypothesize that we may find that mannose supplies more properly glycosylated protein substrate and helps expedite protein synthesis, that excess mannose leads to alternative glycan structures which confer improved stability, or that there are new sites that become glycosylated after mannose supplementation.
Primary Outcome
Glycopeptide mass spectrometry will be applied to the major glycoproteins present in serum.
Interventions
- DIETARY_SUPPLEMENT Mannose
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2024-10-29 |
| Est. Completion | 2024-11-06 |
| Phase | NA |
What the finished NCT06507735 record still lists
NCT06507735 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Mannose is the first listed.
NCT06507735 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06507735 about?
NCT06507735 is a clinical study titled "The Effects of Mannose Supplementation on Glycosylation and Protein Levels in Human Sera". The purpose of our study is to investigate the effects of supplemental mannose on sera of humans who are healthy. We will perform proteomics studies to elucidate changes to glycan structure and protein level changes. We hypothesize that we may find that mannose supplies more properly glycosylated pr...
What is the current status of trial NCT06507735?
This trial is currently completed. It is a NA study. The enrollment target is 6 participants. The study started on 2024-10-29. Estimated completion is 2024-11-06.
What interventions are being tested in trial NCT06507735?
The interventions under investigation include: Mannose (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT06507735?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06507735's enrollment target sits among peer trials
6 1983rd of 2000 higher than 13 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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