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NCT06495190 · ClinicalTrials.gov registry record · NA
Cognition, Flavonoids, Exercise, Gut Microbiome
A NA study of Cognitive Decline, Mild, sponsored by Appalachian State University.
- Recruiting
- Registry status
- NA
- Development phase
- 240
- Enrollment target
- 1
- Study location
NCT06495190: Recruiting NA study of Cognitive Decline, Mild, sponsored by Appalachian State University.
NCT06495190 is a NA study of Cognitive Decline, Mild that is actively recruiting participants, run by Appalachian State University. The registered enrollment target is 240 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06495190, a NA study of Cognitive Decline, Mild, is actively recruiting participants, sponsored by Appalachian State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 240 participants
- Enrollment target
- 1
- Study location
Study Summary
This NIH project will examine the effects of routine flavonoid-rich blueberry intake (12-weeks), combined with or in the absence of regular moderate exercise, on cognitive function in a clinical population of older participants identified as experiencing age-related cognitive changes. This project's hypothesis is that the combination of flavonoid-rich diet and routine physical activity may potentiate cognitive benefits and reduce cognitive decline in an aging population, via mechanisms mediated by the gut microbiome.
Primary Outcome
Cognitive function using the Cambridge Neuropsychological Test Assessment Battery (CANTAB, Cambridge Cognition, Ltd).
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Placebo
- BEHAVIORAL Stretching
- BEHAVIORAL Walking
- DIETARY_SUPPLEMENT Blueberry
Study Locations (1)
North Carolina
- Appalachian State University Human Performance Lab, North Carolina Research Campus - Kannapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 240 participants |
| Start Date | 2025-01-01 |
| Est. Completion | 2028-12-31 |
| Phase | NA |
What NCT06495190 shows while recruiting
NCT06495190 is an interventional study that assigns participants to a tested intervention. The registered 240 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (83% lower).
The record links to 1 condition, with Cognitive Decline, Mild appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.
NCT06495190 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06495190 about?
NCT06495190 is a clinical study titled "Cognition, Flavonoids, Exercise, Gut Microbiome". This NIH project will examine the effects of routine flavonoid-rich blueberry intake (12-weeks), combined with or in the absence of regular moderate exercise, on cognitive function in a clinical population of older participants identified as experiencing age-related cognitive changes. This project's...
What is the current status of trial NCT06495190?
This trial is currently recruiting. It is a NA study. The enrollment target is 240 participants. The study started on 2025-01-01. Estimated completion is 2028-12-31.
What conditions does trial NCT06495190 study?
This clinical trial studies the following conditions: Cognitive Decline, Mild.
What interventions are being tested in trial NCT06495190?
The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Stretching (BEHAVIORAL), Walking (BEHAVIORAL), Blueberry (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT06495190?
This trial is sponsored by Appalachian State University, which has 37 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06495190 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06495190's enrollment target sits among peer trials
240 440th of 2000 higher than 1,542 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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